28562-61-0Relevant articles and documents
Synthesis and property of novel amino acid-based polymers by self-polyaddition of monomers containing both oxetanyl and carboxyl groups
Kudo, Hiroto,Ohshiro, Toshiki,Atsumi, Hiroyuki,Kamio, Ayako,Nishikubo, Tadatomi,Murakami, Saeko
, p. 458 - 465 (2012)
A new synthetic strategy for polymers containing amino acids in the main chain was developed. Monomers N-oxetanylalanine (N-Oxe-Ala-COOH), N-oxetanylglutamic acid (N-Oxe-Glu-COOH), and N-oxetanyllysine (N-Oxe-Lys-COOH) containing both oxetanyl and carboxyl groups were synthesized, and self-polyaddition and self-copolyaddition of these monomers afforded the corresponding polymers containing amino acids in the main chain [poly( OxAla), poly(OxLys), poly(OxGlu), poly( OxAla-co-OxGlu), poly(OxGlu-co- OxLys), and poly(OxAla-co-OxLys)] with molecular weight in the range of 920-6620, in satisfactory yields. The physical properties, such as solubility, glass transition temperature, and thermal stability, were consistent with the amount of carboxyl groups at the chain ends. Biodegradability of the polymers was examined by the biochemical oxygen demand method; the decomposition ratios of poly(OxAla) and poly( OxAla-co-OxGlu) were about 60%, whereas that of poly( OxGlu) was nearly 100% after 28 days. 2011 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem, 2011 This article reports the development of new strategy for polymers containing amino acids in the main chain. Monomers containing both oxetanyl and carboxyl groups were synthesized derived from amino acids, and self-polyaddition and self-copolyaddition of these monomers afforded the corresponding polymers containing amino acids in the main chain. The obtained amino -acid- based polymers had good solubility, high- glass transition temperature, high thermal stability, and good biodegradability. Copyright
Process for the preparation of 2,2-bis-chloro-methylalkanecarboxylic acid chlorides
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, (2008/06/13)
A process for the preparation of a 2,2-bis-chloro-methyl-alkanecarboxylic acid of the formula STR1 in which R is hydrogen, alkyl, cycloalkyl or optionally substituted phenyl, which comprises reacting an oxetane-3-carboxylic acid of the formula STR2 or a salt thereof, with an inorganic acid chloride at a temperature between 20° C. and the boiling point of the reaction mixture. The products are known intermediates for fungicides and herbicides.