28586-46-1

Basic information

• Product Name: N-{4-chloro-2-[hydroxy(phenyl)methyl]phenyl}acetamide
• CAS NO: 28586-46-1
• Molecular Formula: C₁₅H₁₄ClNO₂
• Molecular Weight: 275.7302
• Mol File: 28586-46-1.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 488.6°C at 760 mmHg
• Flash Point: 249.3°C
• Density: 1.299g/cm³
• Vapor Pressure: 2.31E-10mmHg at 25°C
• Refractive Index: 1.638
• CAS DataBase Reference: N-{4-chloro-2-[hydroxy(phenyl)methyl]phenyl}acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-{4-chloro-2-[hydroxy(phenyl)methyl]phenyl}acetamide(28586-46-1)
• EPA Substance Registry System: N-{4-chloro-2-[hydroxy(phenyl)methyl]phenyl}acetamide(28586-46-1)

Safety Data

• Hazardous Substances Data: 28586-46-1(Hazardous Substances Data)

Upstream product

• 13788-59-5 N-(2-benzoyl-4-chlorophenyl)acetamide 

Relevant articles and documents

Ureas in Organic Synthesis. XII. Syntesis of 2-Amino-5-chlorobenzhydrylureas and Their Heterocyclization

A synthetic method was developed for hard-to-get biologically active 2-amino-5-chlorobenzhydrylureas based on reaction of the corresponding benzhydrols with urea in sulfuric acid. The 2-amino-5-chlorobenzhydrylureas were shown to easily undergo on heating cyclization to 1-R-1,2,3,4-tetrahydro-4-phenyl-chloroquinazolin-2-ones.