285985-01-5Relevant academic research and scientific papers
3-benzyl-2-(4-fluorophenyl)-1,3-thiazolidin-4-one
Gutierrez, Alexander,Insuasty, Braulio,Cobo, Justo,Glidewell, Christopher
, p. o10-o12 (2011)
The title compound, C16H14FNOS, crystallizes with Z′ = 2 in the space group P21/c. In one of the two independent molecules, the heterocyclic ring is effectively planar, but in the other molecule this ring adopts an envelope conformation. The molecules are weakly linked by two C - H...O hydrogen bonds to form C2 2(14) chains. Comparisons are made with some symmetrically substituted 2-aryl-3-benzyl-1,3-thiazoli-din-4-ones.
THIAZOLIDINONE COMPOUNDS AND USE THEREOF
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Paragraph 0894-0895, (2017/09/21)
A pharmaceutical composition containing a compound of Formula (I) for treating an opioid receptor-associated condition. Also disclosed is a method for treating an opioid receptor-associated condition using such a compound. Further disclosed are two sets of thiazolidinone compounds of formula (I): (i) compounds each having an enantiomeric excess greater than 90% and (ii) compounds each being substituted with deuterium.
