286-44-2Relevant academic research and scientific papers
Direct and Stereospecific Synthesis of N-H and N-Alkyl Aziridines from Unactivated Olefins Using Hydroxylamine-O-Sulfonic Acids
Ma, Zhiwei,Zhou, Zhe,Kürti, László
supporting information, p. 9886 - 9890 (2017/08/08)
A RhII-catalyzed direct and stereospecific N-H- and N-alkyl aziridination of olefins is reported that uses hydroxylamine-O-sulfonic acids as inexpensive, readily available, and nitro group-free aminating reagents. Unactivated olefins, featuring a wide range of functional groups, are converted into the corresponding N-H or N-alkyl aziridines in good to excellent yields. This operationally simple, scalable transformation proceeds efficiently at ambient temperature and is tolerant towards oxygen and trace moisture.
Compounds with Bridgehead Nitrogen. Part 43. The Reaction between trans-2-Aminocycloalkanethiols and Formaldehyde
Barkworth, Peter M. R.,Crabb, Trevor A.
, p. 2777 - 2782 (2007/10/02)
trans-2-Aminocyclopentanethiol condenses with formaldehyde to give rel-(3aR,6aR,9aR,12aR)-6,12-methanoperhydrodicyclopentanodithiadiazecine, whereas trans-2-aminocyclohexanethiol and trans-2-aminocycloheptanethiol give 1:1 mixture of diastereomeric bis(perhydrocycloalkanothiazol-3-yl)methanes.
