286013-39-6Relevant academic research and scientific papers
6-Azapyrimidine-2′-deoxy-4′-thionucleosides: Antiviral agents against TK+ and TK- HSV and VZV strains
Maslen, Hannah L.,Hughes, David,Hursthouse, Mike,De Clercq, Erik,Balzarini, Jan,Simons, Claire
, p. 5482 - 5491 (2004)
The synthesis of a series of novel 1-(2-deoxy-4-thio-β-D-erythro- pentofuranosyl)-(6-azapyrimidine) nucleosides is described. X-ray crystallographic data of the thymidine derivative allowed conformational analysis, which indicated a twist (3Ts
Synthesis of 4-thiofuranoid 1,2-glycals and their application to stereoselective synthesis of 4'-thionucleosides
Miller, J. Allen,Pugh, Ashley W.,Ullah, G. Mustafa
, p. 3265 - 3268 (2007/10/03)
Convenient one-pot procedures using iodine monochloride have been developed for the preparation of two 4-thio-1,2-glycals from readily available starting materials and for their β-anomer selective conversion into 2'-iodo-4'-thionucleosides. Conditions for
