28623-31-6

Basic information

• Product Name: N,N-di(propan-2-yl)-1,3,2-dioxaphospholan-2-amine
• Synonyms: 1,3,2-Dioxaphospholan-2-amine, N,N-bis(1-methylethyl)-; 1,3,2-Dioxaphospholidine, diisopropylamino-
• CAS NO: 28623-31-6
• Molecular Formula: C₈H₁₈NO₂P
• Molecular Weight: 191.2078
• Mol File: 28623-31-6.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 150.5°C at 760 mmHg
• Flash Point: 44.8°C
• Vapor Pressure: 3.84mmHg at 25°C
• CAS DataBase Reference: N,N-di(propan-2-yl)-1,3,2-dioxaphospholan-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-di(propan-2-yl)-1,3,2-dioxaphospholan-2-amine(28623-31-6)
• EPA Substance Registry System: N,N-di(propan-2-yl)-1,3,2-dioxaphospholan-2-amine(28623-31-6)

Safety Data

• Hazardous Substances Data: 28623-31-6(Hazardous Substances Data)

Upstream product

• 822-39-9 2-chloro-1,3,2-dioxaphospholan 
• 108-18-9 diisopropylamine 

Downstream Products

• 40928-00-5 isopropyl ethylene phosphite 
• 108-18-9 diisopropylamine 
• 220995-96-0 2-Diisopropyl-2-N'-(4-nitrobenzyl)imino-1,3,2-λ⁵-dioxaphospholane 
• 220995-84-6 2-Diisopropylamino-2-N-phenylimino-1,2,3-λ⁵-dioxaphospholane 
• 220995-86-8 2-N-Benzylimino-2-diisopropyl-1,3,2-λ⁵-dioxaphospholane 

Relevant articles and documents

Phosphoric acid phaseomannite class compound and its preparation method and application (by machine translation)

The invention discloses a phaseomannite class phosphate compound, phosphoric acid phaseomannite class compound preparation method, and these phosphoric acid phaseomannite class compounds in the preparation of an anti-tumor drug. The use of non-small cell lung cancer cells to the compounds of this invention to inhibit the growth of tumor cells in active testing, that the compounds of this invention have high inhibition of tumor cell growth activity, some of the compound inhibiting activity even with cisplatin active quite, which indicates that the compounds of this invention have good cell penetrability and phosphorus esterase stability, can be used for the development of anti-tumor medicament. (by machine translation)

Preparation of phospholipid analogues using the phosphoramidite route

The phosphoramidite route has been used to prepare phospholipid analogues possessing biocompatible properties and the monomer 2-(methacryloyIoxy)ethylphosphorylcholine, utilised in the preparation of biocompatible polymers. Modifications to established methodology include, as an alternative to the thermally unstable tetrazole, the use of 4,5-dichloroimidazole as an acid catalyst for preparing phosphite esters from the corresponding phosphoramidites, and the use of trimethylamine N-oxide as oxidant for the conversion of the phosphite esters into the corresponding phosphates. The Royal Society of Chemistry 2000.