286372-71-2Relevant academic research and scientific papers
A general synthesis of (2Z)-terpenoic acids
Cahard, Dominique,Mammeri, Malika,Poirier, Jean-Marie,Duhamel, Lucette
, p. 3619 - 3622 (2000)
A three-step synthesis of (2Z), (4E)-polyenic acids 6 is described. Condensation of aldehydes 1 with potassium prenal enolate led to dihydropyranols 3 which were oxidized into dihydropyrones 5, precursors of (2Z), (4E)-polyenic acids 6. The procedure was applied to a synthesis of 13- cis-retinoic acids from β-ionylidene acetaldehydes. (C) 2000 Elsevier Science Ltd.
