286380-59-4

Upstream product

• 143-33-9 sodium cyanide 
• 215116-42-0 4,4′-bis(chloromethyl)-2,2′-bipyridyl 
• 39891-09-3 (6-chloro-pyridin-3-yl)-acetonitrile 
• 1762-34-1 5,5'-dimethyl-2,2'-bipyridine 

Relevant academic research and scientific papers

Engineering Olefin-Linked Covalent Organic Frameworks for Photoenzymatic Reduction of CO2

It is of profound significance concerning the global energy and environmental crisis to develop new techniques that can reduce and convert CO2. To address this challenge, we built a new type of artificial photoenzymatic system for CO2 reduction, using a rationally designed mesoporous olefin-linked covalent organic framework (COF) as the porous solid carrier for co-immobilizing formate dehydrogenase (FDH) and Rh-based electron mediator. By adjusting the incorporating content of the Rh electronic mediator, which facilitates the regeneration of nicotinamide cofactor (NADH) from NAD+, the apparent quantum yield can reach as high as 9.17±0.44 %, surpassing all reported NADH-regenerated photocatalysts constructed by crystalline framework materials. Finally, the assembled photocatalyst–enzyme coupled system can selectively convert CO2 to formic acid with high efficiency and good reusability. This work demonstrates the first example using COFs to immobilize enzymes for artificial photosynthesis systems that utilize solar energy to produce value-added chemicals.

Reductive couplings of 2-halopyridines without external ligand: Phosphine-free nickel-catalyzed synthesis of symmetrical and unsymmetrical 2,2'-bipyridines

An unexpectedly facile synthetic approach for symmetrical and unsymmetrical 2,2'-bipyridines through the Ni-catalyzed reductive couplings of 2-halopyridines was developed. The couplings were efficiently catalyzed by 5 mol % of NiCl2.6H2O without the use of external ligands. A variety of 2,2'-bipyridines including caerulomycin F have been efficiently synthesized.

Preparation, properties, and reactions of metal-containing heterocycles, 101. Inclusion of copper(I) into a novel bipyridine-containing tetraphosphadiplatinacyclophane

The 5,5'-bis(hydroxyalkyl)-2,2'-bipyridines 4a-c (Scheme 1) were prepared either in one step (4b, 4c) or in four steps (4a) starting with 5,5'-dimethyl-2,2'-bipyridine in each case. Reaction of 4a-c with mesyl chloride afforded the bis(mesylates) [-C5H3N-(CH2)(n)-CH2-OSO2Me]2 5a-c [n = 1 (a), 2 (b), 3 (c)], which could easily be transformed into the diphosphanes 6a-c by reaction with LiPPh2. Treatment of 6c, 6b with Cl2Pt(NCPh)2 and (RC6H4)2Pt(COD) according to the high-dilution method resulted in the formation of the tetraphosphadiplatinacyclophanes [-C5H3N- (CH2)4-PPh2PtCl2PPh2-(CH2)4-C5H3N-]2 (7c) and [-C5H3N-(CH2)3- PPh2Pt(C6H4R)2-PPh2-(CH2)3-C5H3N-]2 (8b, 9b) (8b: R = H, 9b: R = tBu), respectively (Scheme 2). The molecular structures of 8b and 9b were elucidated by X-ray structural analyses. The noncoordinated bipyridine moieties in 8b were employed to encapsulate copper(I)to give the host/guest complex 10b (Scheme 3), which was investigated by FAB-MS, NMR spectroscopy, and cyclovoltammetry. 10b exhibited a quasi-reversible oxidation at E(1/2) = -0.31 V and an electrodeposition-redissolution redox system at E(1/2) = - 0.79 V, owing to the formation of copper at the surface of the working electrode.