286458-66-0Relevant articles and documents
Efficient synthesis of the C1-C11 fragment of the tedanolides. The nonaldol aldol process in synthesis
Jung, Michael E.,Marquez, Rodolfo
, p. 1669 - 1672 (2000)
(matrix presented) The nonaldol aldol process developed in our laboratories has been applied to the synthesis of a C1-C11 fragment 22 of the novel macrocyclic cytotoxic agents tedanolide and 13-deoxytedanolide 1 and 2. The commercially available hydroxy ester 7 was converted in 24 steps into compound 22 using two nonaldol aldol reactions.