2866-68-4

Upstream product

• 7148-07-4 1-pyrrolidinocyclopent-1-ene 
• 104-83-6 1-Chloro-4-(chloromethyl)benzene 
• 10472-24-9 methyl 2-oxocyclopentane-1-carboxylate 
• 115851-73-5 1-[(4-chlorophenyl)methyl]-2-oxocyclopentanecarboxylic acid methyl ester 
• 622-95-7 4-chlorobenzyl bromide 

Downstream Products

• 1213265-78-1 2-(4-chlorobenzyl)-5-isopropylidenecyclopentanone 
• 2700-03-0 3-<1-(4-Chlor-benzyl)-2-oxo-cyclopentyl>-propionsaeure 
• 2700-11-0 2-<4-Chlor-benzyl>-2-<2-cyan-aethyl>-cyclopentanon 
• 73403-11-9 2-(4-Chloro-benzyl)-2,5,5-trimethyl-cyclopentanone 

Relevant academic research and scientific papers

PRODUCTION METHOD FOR CARBONYL COMPOUND

The present invention is to provide a method of producing a carbonyl compound at a higher yield. The method of producing a carbonyl compound according to the present invention produces a carbonyl compound represented by general formula (I) by subjecting a compound represented by general formula (II) to dealkoxycarbonylation in the presence of an organic carboxylic acid salt of a tertiary amine. In the formula, R represents an alkyl group having from 1 to 4 carbons.

PRODUCTION METHOD OF CARBONYL COMPOUND

The present invention is to provide a method of producing a carbonyl compound at a higher yield. The method of producing a carbonyl compound according to the present invention produces a carbonyl compound represented by general formula (I) by subjecting a compound represented by general formula (II) to dealkoxycarbonylation in the presence of a hydrogen halide salt of tertiary amine. In the formula, R represents an alkyl group having from 1 to 4 carbons.

PRODUCTION METHOD FOR CYCLOPENTANONE DERIVATIVE, INTERMEDIATE COMPOUND, AND PRODUCTION METHOD FOR INTERMEDIATE COMPOUND

The present invention is a production method for a compound represented by the following general formula (V), the method comprising a step of obtaining a compound represented by the following general formula (II) by reacting a compound represented by the following general formula (I) with an acid: wherein, G1 and G2 are each a protecting group that dissociates under acidic conditions.

Process for preparation of azolylmethylcycloalkanol derivatives

A process for preparing a derivative of azolylmethylcycloalkanol of the following formula (I) comprising, providing a solid-liquid two-phase mixture of a cycloalkanone derivative of formula (II), an azole compound of formula (III), a metal oxide of formula (IV), and an organic solvent, and adding a sulfonium compound of formula (V) to said solid-liquid two-phase mixture under heating while stirring, STR1 wherein R1 and R2 individually represent a hydrogen atom or an alkyl group; X is a halogen atom, an alkyl group, a haloalkyl group, a phenyl group, a cyano group, or a nitro group; m is an integer of 0 to 5 (when m is 2 or larger, Xs may be either the same or different); n is an integer of 0 to 2; A represents a nitrogen atom or a group CH; M1 represents an alkali metal atom or an alkaline earth metal atom; M2 represents an alkaline earth metal atom, a zinc atom, or two alkali metal atoms; Y represents a halogen atom or a C1 -C4 alkoxysulfonyloxy group; and p denotes an integer of 0 or 1.

Aromatase inhibitors: Synthesis, biological activity, and structure of 1,2-imidazolylmethylcyclopentanol derivatives

Two series of 1,2-disubstituted imidazolylmethylcyclopentanol derivatives (5a-d, 10a-d) were prepared by using easily available methyl 2- oxocyclopentanecarboxylate as the starting material. Evaluation of the aromatase inhibitory activities in vitro was p