2866-68-4

Basic information

• Product Name: Cyclopentanone, 2-[(4-chlorophenyl)methyl]-
• CAS NO: 2866-68-4
• Molecular Formula: C12H13ClO
• Molecular Weight: 208.688
• Mol File: 2866-68-4.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Cyclopentanone, 2-[(4-chlorophenyl)methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclopentanone, 2-[(4-chlorophenyl)methyl]-(2866-68-4)
• EPA Substance Registry System: Cyclopentanone, 2-[(4-chlorophenyl)methyl]-(2866-68-4)

Safety Data

• Hazardous Substances Data: 2866-68-4(Hazardous Substances Data)

Upstream product

• 622-95-7 4-chlorobenzyl bromide 
• 10472-24-9 methyl 2-oxocyclopentane-1-carboxylate 
• 115851-73-5 1-[(4-chlorophenyl)methyl]-2-oxocyclopentanecarboxylic acid methyl ester 
• 7148-07-4 1-pyrrolidinocyclopent-1-ene 
• 104-83-6 1-Chloro-4-(chloromethyl)benzene 

Downstream Products

• 1213265-78-1 2-(4-chlorobenzyl)-5-isopropylidenecyclopentanone 
• 2700-03-0 3-<1-(4-Chlor-benzyl)-2-oxo-cyclopentyl>-propionsaeure 
• 2700-11-0 2-<4-Chlor-benzyl>-2-<2-cyan-aethyl>-cyclopentanon 
• 73403-11-9 2-(4-Chloro-benzyl)-2,5,5-trimethyl-cyclopentanone 

Relevant articles and documents

PRODUCTION METHOD FOR CARBONYL COMPOUND

The present invention is to provide a method of producing a carbonyl compound at a higher yield. The method of producing a carbonyl compound according to the present invention produces a carbonyl compound represented by general formula (I) by subjecting a compound represented by general formula (II) to dealkoxycarbonylation in the presence of an organic carboxylic acid salt of a tertiary amine. In the formula, R represents an alkyl group having from 1 to 4 carbons.

PRODUCTION METHOD FOR CYCLOPENTANONE DERIVATIVE, INTERMEDIATE COMPOUND, AND PRODUCTION METHOD FOR INTERMEDIATE COMPOUND

The present invention is a production method for a compound represented by the following general formula (V), the method comprising a step of obtaining a compound represented by the following general formula (II) by reacting a compound represented by the following general formula (I) with an acid: wherein, G1 and G2 are each a protecting group that dissociates under acidic conditions.

Aromatase inhibitors: Synthesis, biological activity, and structure of 1,2-imidazolylmethylcyclopentanol derivatives

Two series of 1,2-disubstituted imidazolylmethylcyclopentanol derivatives (5a-d, 10a-d) were prepared by using easily available methyl 2- oxocyclopentanecarboxylate as the starting material. Evaluation of the aromatase inhibitory activities in vitro was p