28660-33-5

Usage

Uses

Used in Water Treatment:
(2-aminopropyl)phosphonic acid is used as a chelating agent for metal ion sequestration, which helps in the removal of metal ions from water, making it suitable for water treatment applications.
Used in Corrosion Inhibition:
(2-aminopropyl)phosphonic acid is used as a corrosion inhibitor to prevent the corrosion of metal surfaces, making it useful in various industrial processes.
Used in Pharmaceutical Synthesis:
(2-aminopropyl)phosphonic acid is used as a reagent in the synthesis of pharmaceuticals, contributing to the development of new drugs and medications.
Used in Organic Compound Synthesis:
(2-aminopropyl)phosphonic acid is used as a reagent in the synthesis of organic compounds, aiding in the production of various chemical products.
Used in Research as a Catalyst or Reagent:
(2-aminopropyl)phosphonic acid is used as a catalyst or reagent in research, facilitating various chemical reactions and experiments.
Used in Flame Retardant Development:
(2-aminopropyl)phosphonic acid has potential applications in the development of flame retardants, which can be used to enhance the fire resistance of materials.
Used in Adhesive Production:
(2-aminopropyl)phosphonic acid has potential applications in the production of adhesives, contributing to the development of new adhesive formulations with improved properties.

Upstream product

• 1067-71-6 Diethyl (2-oxopropyl)phosphonate 
• 53327-57-4 diethyl 2-aminopropylphosphonate 
• 151397-36-3 (S)-diethyl 2-aminopropanephosphonate 
• 88129-50-4 [(R)-2-(Toluene-4-sulfonylamino)-propyl]-phosphonic acid diethyl ester 
• 72696-73-2 [2-(Diethoxy-phosphorylamino)-propyl]-phosphonic acid diethyl ester 
• 151397-26-1 diethyl (1RS,2S)-1-hydroxy-2-(phthalimido)propylphosphonate 

Relevant academic research and scientific papers

An efficient synthesis of N-phosphorylated azadienes, primary (E)-allylamines, and ss-amino-phosphane oxides and -phosphonates from ss-functionalized oxime derivatives

A simple and stereoselective synthesis of primary (E)-allylamines 1 and 1-azadienes 5, 7 is reported. N-Phosphorylated azadienes 5 and 7 are obtained by addition of phosphorus chlorides 3 to unsaturated oximes 2, while azadienes 24 are prepared by olefination reactions of functionalized enamines 20/21. Reduction of azadienes 5, 7, 24 and derivatives 13/14 and 20/21 with hydrides, followed by deprotection of the resulting amines leads to the formation of primary allylamines 1 and ss-aminophosphane oxides 17, phosphonates 18, and phosphonic acid derivatives 19.

Preparation of 1-aminoalkylphosphonic acids and 2-aminoalkylphosphonic acids by reductive amination of oxoalkylphosphonates

By reacting dialkyl 1-oxo- or 2-oxoalkylphosphonates with benzhydrylamine followed by reduction with triacetoxyborohydride and acid hydrolysis gave corresponding aminoalkylphosphonic acids with satisfactory yields. The use of benzylamine, α-methylbenzylamine and tritylamine was unsuccessful in the case of dialkyl 1-oxoalkylphosphonates whereas conversion of 2-oxoalkylphosphonates was also achieved although with lower yields.

ACCESS A L'ACIDE AMINO-2 PROPYLPHOSPHONIQUE OPTIQUEMENT ACTIF

The reaction of optically active α-methylbenzylamine with phosphonates containing an unsaturated carbon in the β position results in a mixture of cis- and trans-aminovinylphosphonates.Reduction with NaBH4/CH3COOH/THF produces benzylaminopropylphosphonates

PREPARATION OF OPTICALLY ACTIVE 2-AMINOALKYLPHOSPHINIC AND PHOSPHONIC ACIDS

The reaction of sodium alkylphosphinates or sodium dialkylphosphonates with tosylamino tosylates of amino alcohols derived from 1-aminoalkylcarboxylic acids gives high yields of optically active 2-tosylaminoalkylphosphinic or phosphonic esters.

ANIMATION REDUCTRICE DES β-CETOPHOSPHONATES: PREPARATION D'ACIDES AMINOALKYLPHOSPHONIQUES

Diethyl 2-oxo-alkylphosphonates undergo reductive amination in the presence of an amine and sodium cyanohydridoborate (NaBH3CN) in MeOH at Ph 7-7.5.Studies with a large variety of ketophosphonates show that the reaction rate is very sensitive to steric hi