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(2-aminopropyl)phosphonic acid, also known as APNA, is an organophosphorus compound characterized by a phosphonic acid with an amino group attached to the carbon atom of the propyl group. It is a versatile and important chemical with a wide range of practical uses in different industries.

28660-33-5

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28660-33-5 Usage

Uses

Used in Water Treatment:
(2-aminopropyl)phosphonic acid is used as a chelating agent for metal ion sequestration, which helps in the removal of metal ions from water, making it suitable for water treatment applications.
Used in Corrosion Inhibition:
(2-aminopropyl)phosphonic acid is used as a corrosion inhibitor to prevent the corrosion of metal surfaces, making it useful in various industrial processes.
Used in Pharmaceutical Synthesis:
(2-aminopropyl)phosphonic acid is used as a reagent in the synthesis of pharmaceuticals, contributing to the development of new drugs and medications.
Used in Organic Compound Synthesis:
(2-aminopropyl)phosphonic acid is used as a reagent in the synthesis of organic compounds, aiding in the production of various chemical products.
Used in Research as a Catalyst or Reagent:
(2-aminopropyl)phosphonic acid is used as a catalyst or reagent in research, facilitating various chemical reactions and experiments.
Used in Flame Retardant Development:
(2-aminopropyl)phosphonic acid has potential applications in the development of flame retardants, which can be used to enhance the fire resistance of materials.
Used in Adhesive Production:
(2-aminopropyl)phosphonic acid has potential applications in the production of adhesives, contributing to the development of new adhesive formulations with improved properties.

Check Digit Verification of cas no

The CAS Registry Mumber 28660-33-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,8,6,6 and 0 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 28660-33:
(7*2)+(6*8)+(5*6)+(4*6)+(3*0)+(2*3)+(1*3)=125
125 % 10 = 5
So 28660-33-5 is a valid CAS Registry Number.

28660-33-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-aminopropylphosphonic acid

1.2 Other means of identification

Product number -
Other names (2-aminopropyl)phosphonic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:28660-33-5 SDS

28660-33-5Downstream Products

28660-33-5Relevant academic research and scientific papers

An efficient synthesis of N-phosphorylated azadienes, primary (E)-allylamines, and ss-amino-phosphane oxides and -phosphonates from ss-functionalized oxime derivatives

Palacios, Francisco,Aparicio, Domitila,Garcia, Jesus,Rodriguez, Encina

, p. 1413 - 1423 (2007/10/03)

A simple and stereoselective synthesis of primary (E)-allylamines 1 and 1-azadienes 5, 7 is reported. N-Phosphorylated azadienes 5 and 7 are obtained by addition of phosphorus chlorides 3 to unsaturated oximes 2, while azadienes 24 are prepared by olefination reactions of functionalized enamines 20/21. Reduction of azadienes 5, 7, 24 and derivatives 13/14 and 20/21 with hydrides, followed by deprotection of the resulting amines leads to the formation of primary allylamines 1 and ss-aminophosphane oxides 17, phosphonates 18, and phosphonic acid derivatives 19.

Preparation of 1-aminoalkylphosphonic acids and 2-aminoalkylphosphonic acids by reductive amination of oxoalkylphosphonates

Ryglowski, Artur,Kafarski, Pawel

, p. 10685 - 10692 (2007/10/03)

By reacting dialkyl 1-oxo- or 2-oxoalkylphosphonates with benzhydrylamine followed by reduction with triacetoxyborohydride and acid hydrolysis gave corresponding aminoalkylphosphonic acids with satisfactory yields. The use of benzylamine, α-methylbenzylamine and tritylamine was unsuccessful in the case of dialkyl 1-oxoalkylphosphonates whereas conversion of 2-oxoalkylphosphonates was also achieved although with lower yields.

ACCESS A L'ACIDE AMINO-2 PROPYLPHOSPHONIQUE OPTIQUEMENT ACTIF

Sauveur, F.,Collignon, N.,Guy, A.,Savignac, Ph.

, p. 341 - 346 (2007/10/02)

The reaction of optically active α-methylbenzylamine with phosphonates containing an unsaturated carbon in the β position results in a mixture of cis- and trans-aminovinylphosphonates.Reduction with NaBH4/CH3COOH/THF produces benzylaminopropylphosphonates

PREPARATION OF OPTICALLY ACTIVE 2-AMINOALKYLPHOSPHINIC AND PHOSPHONIC ACIDS

Duggan, Mark E.,Karanewsky, Donald S.

, p. 2935 - 2938 (2007/10/02)

The reaction of sodium alkylphosphinates or sodium dialkylphosphonates with tosylamino tosylates of amino alcohols derived from 1-aminoalkylcarboxylic acids gives high yields of optically active 2-tosylaminoalkylphosphinic or phosphonic esters.

ANIMATION REDUCTRICE DES β-CETOPHOSPHONATES: PREPARATION D'ACIDES AMINOALKYLPHOSPHONIQUES

Varlet, J. M.,Collignon, N.,Savignac, Ph.

, p. 3713 - 3721 (2007/10/02)

Diethyl 2-oxo-alkylphosphonates undergo reductive amination in the presence of an amine and sodium cyanohydridoborate (NaBH3CN) in MeOH at Ph 7-7.5.Studies with a large variety of ketophosphonates show that the reaction rate is very sensitive to steric hi

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