28679-16-5

Basic information

• Product Name: TRIMETHYLHEXAMETHYLENE DIISOCYANATE
• Synonyms: 1,6-diisocyanatotrimethylhexane;diisocyanatedetrimethyleetdehexamethylene;trimethylhexamethyleneisocyanate;TMDI;TRIMETHYLHEXAMETHYLENE DIISOCYANATE;Diisocyanatotrimethylhexyl;Trimethylhexamethylene diisocyanate (2,2,4- and 2,4,4- mixtures);trimethylhexa-1,6-diyl diisocyanate
• CAS NO: 28679-16-5
• Molecular Formula: C11H18N2O2
• Molecular Weight: 210.27
• EINECS: 249-151-6
• Mol File: 28679-16-5.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 149°C
• Flash Point: 114.6°C
• Appearance: /
• Density: 1,02 g/cm3
• Vapor Pressure: 1.66E-10mmHg at 25°C
• Refractive Index: 1.4620 to 1.4640
• CAS DataBase Reference: TRIMETHYLHEXAMETHYLENE DIISOCYANATE(CAS DataBase Reference)
• NIST Chemistry Reference: TRIMETHYLHEXAMETHYLENE DIISOCYANATE(28679-16-5)
• EPA Substance Registry System: TRIMETHYLHEXAMETHYLENE DIISOCYANATE(28679-16-5)

Safety Data

• Hazard Codes: T
• Statements: 23/24/25-40-42-36/37/38-23
• Safety Statements: 26-36/37/39-45-38-28
• RIDADR: 2206
• HazardClass: 6.1
• PackingGroup: III
• Hazardous Substances Data: 28679-16-5(Hazardous Substances Data)

Usage

Description

TRIMETHYLHEXAMETHYLENE DIISOCYANATE, also known as TMHDI, is a colorless liquid with a density greater than water. It is insoluble in water and can cause irritation upon contact with the skin, eyes, and mucous membranes. Ingestion of TMHDI may result in toxicity. TRIMETHYLHEXAMETHYLENE DIISOCYANATE is primarily used as a precursor in the production of various chemicals.

Uses

Used in Chemical Synthesis:
TRIMETHYLHEXAMETHYLENE DIISOCYANATE is used as a chemical intermediate for the synthesis of various chemicals. Its application reason is to serve as a starting material for the production of a wide range of chemical products, including polyurethanes, elastomers, and other specialty chemicals.
Used in the Polyurethane Industry:
TRIMETHYLHEXAMETHYLENE DIISOCYANATE is used as a monomer for the production of polyurethane materials. Its application reason is to provide unique properties such as flexibility, durability, and resistance to abrasion, making it suitable for a variety of applications, including foams, adhesives, sealants, and coatings.
Used in the Elastomer Industry:
TRIMETHYLHEXAMETHYLENE DIISOCYANATE is used as a key component in the manufacturing of elastomers. Its application reason is to enhance the performance characteristics of elastomers, such as their elasticity, resilience, and resistance to various environmental factors, which are essential for their use in automotive, industrial, and consumer products.
Used in the Pharmaceutical Industry:
TRIMETHYLHEXAMETHYLENE DIISOCYANATE is used as a building block for the synthesis of certain pharmaceutical compounds. Its application reason is to contribute to the development of new drugs with specific therapeutic properties, potentially benefiting various medical treatments and healthcare applications.

Air & Water Reactions

Insoluble in water and denser than water. Reacts with water or moisture in the air to form carbon dioxide and the corresponding diamine (USCG 1991).

Reactivity Profile

Isocyanates and thioisocyanates, such as TRIMETHYLHEXAMETHYLENE DIISOCYANATE, are incompatible with many classes of compounds, reacting exothermically to release toxic gases. Reactions with amines, aldehydes, alcohols, alkali metals, ketones, mercaptans, strong oxidizers, hydrides, phenols, and peroxides can cause vigorous releases of heat. Acids and bases initiate polymerization reactions in these materials. Some isocyanates react with water to form amines and liberate carbon dioxide.

Health Hazard

CALL FOR MEDICAL AID. VAPOR: POISONOUS. MAY BE FATAL IF INHALED OR ABSORBED THOUGH SKIN. Contact may cause burns to skin and eyes. Move to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. LIQUID: POISONOUS. MAY BE FATAL IF SWALLOWED OR ABSORBED THROUGH SKIN: Contact may burn skin and eyes. Immediately flush skin or eyes with running water for at least 15 minutes. Speed in removing from skin is of extreme importance. Remove and isolate contaminated clothing and shoes at the site. Keep victim quiet and maintain normal body temperature. Effects may be delayed; keep victim under observation. If swallowed and victim is UNCONSCIOUS OR HAVING CONVULSIONS, do nothing except keep victim warm. INHALATION: Poisonous; may be fatal if inhaled. SKIN and EYES: May cause burns. Poisonous, may be fatal if absorbed though skin. INGESTION: Poisnous; May be fatal if swallowed.

Fire Hazard

Combustible POISONOUS GASES ARE PRODUCED IN FIRE. Undergoes decomposition to yield toxic fumes including NOx, and TRIMETHYLHEXAMETHYLENE DIISOCYANATE may react violently with alcohols in the presence of a base.

InChI:InChI=1/2C11H18N2O2/c1-10(7-13-9-15)6-11(2,3)4-5-12-8-14;1-10(4-5-12-8-14)6-11(2,3)7-13-9-15/h2*10H,4-7H2,1-3H3