286930-74-3

Basic information

• Product Name: N-(4-fluorocinnamoyl)-2-hydroxy-2-trifluoromethyl-(3,4-methylenedioxyphenyl)ethylamine
• Synonyms: N-(4-fluorocinnamoyl)-2-hydroxy-2-trifluoromethyl-(3,4-methylenedioxyphenyl)ethylamine
• CAS NO: 286930-74-3
• Molecular Weight: 397.326
• Mol File: 286930-74-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(4-fluorocinnamoyl)-2-hydroxy-2-trifluoromethyl-(3,4-methylenedioxyphenyl)ethylamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-fluorocinnamoyl)-2-hydroxy-2-trifluoromethyl-(3,4-methylenedioxyphenyl)ethylamine(286930-74-3)
• EPA Substance Registry System: N-(4-fluorocinnamoyl)-2-hydroxy-2-trifluoromethyl-(3,4-methylenedioxyphenyl)ethylamine(286930-74-3)

Safety Data

• Hazardous Substances Data: 286930-74-3(Hazardous Substances Data)

Upstream product

• 13565-08-7 (E)-3-(4-fluorophenyl)acryloyl chloride 
• 792895-22-8 2-hydroxy-2-trifluoromethyl-(3,4-methylenedioxyphenyl)ethylamine 
• 102124-73-2 α,α,α-trifluoro-3,4-methylenedioxyacetophenone 
• 17680-04-5 (3,4-methylenedioxy)phenylmagnesium bromide 

Relevant articles and documents

Unusual behaviour of N-cinnamoyl-2-hydroxy-2- (trifluoromethyl)arylethylamines in Pictet-Gams cyclization. Synthesis of 2- styryl-5-aryl-5-trifluoromethyl-2-oxazolines

Cyclization of N-acyl-2-hydroxy-2-(trifluoromethyl)arylethylamines 4 under Pictet-Gams conditions afforded 2-oxazolines 5 instead of the expected isoquinolines 6. The effect of the trifluoromethyl group on the result of the reaction is discussed.