286931-55-3

Basic information

• Product Name: methyl 3-(3-chloro-2,5-dimethoxyphenyl)-3-oxopropionate
• Synonyms: methyl 3-(3-chloro-2,5-dimethoxyphenyl)-3-oxopropionate
• CAS NO: 286931-55-3
• Molecular Weight: 272.685
• Mol File: 286931-55-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl 3-(3-chloro-2,5-dimethoxyphenyl)-3-oxopropionate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 3-(3-chloro-2,5-dimethoxyphenyl)-3-oxopropionate(286931-55-3)
• EPA Substance Registry System: methyl 3-(3-chloro-2,5-dimethoxyphenyl)-3-oxopropionate(286931-55-3)

Safety Data

• Hazardous Substances Data: 286931-55-3(Hazardous Substances Data)

Upstream product

• 286931-53-1 1-(3-chloro-2-hydroxy-5-methoxyphenyl)ethanone 
• 705-15-7 1-(2-hydroxy-5-methoxyphenyl)ethan-1-one 
• 616-38-6 carbonic acid dimethyl ester 
• 286931-54-2 3'-chloro-2',5'-dimethoxyacetophenone 

Relevant articles and documents

The synthesis of kermesic acid by acetylation-aided tautomerism of 6-chloro-2,5,8-trihydroxynaphtho-1,4-quinone

Methodology has been sought towards obtaining a 2-chloro-1,4-naphthoquinone bearing hydroxyl groups in the adjoining ring for obtaining either kermesic or carminic acids. In the first of these objectives, kermesic acid has been synthesised from 6-chloro-2,5,8-trihydroxynaphtho-1,4-quinone by the regioselective cycloaddition of the 1,2-diacetate formed by its acetylation-aided tautomerism and cycloaddition with (E)- and (Z)-3-alkoxycarbonyl-2,4-bis(trimethylsilyloxy)penta-1,3-dienes. The parent unacetylated quinone resists cycloaddition.