286943-65-5

Usage

Structure

Bicyclic amidine

Molecular structure

Unique

Potential applications

Organic synthesis, catalyst in chemical reactions

Possible uses

Ligand in metal-catalyzed reactions, chiral catalyst in asymmetric synthesis, base in organic reactions

Ability

Form stable complexes with various metal ions

Value

Versatile and valuable in chemical research and industrial applications

Upstream product

• 626-55-1 3-Bromopyridine 
• 658-24-2 2,5-diazabicyclo[2.2.2]octane 

Relevant academic research and scientific papers

DIAZABICYCLIC DERIVATIVES AS NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS

Compounds of formula (I) or a pharmaceutically acceptable salt thereof wherein: V is selected from the group consisting of a covalent bond and CH2; W is selected from the group consisting of a covalent bond, CH2and CH2CH2; X is selected from the group consisting of a covalent bond and CH2; Y is selected from the group consisting of a covalent bond, CH2, and CH2CH2; Z is selected from the group consisting of CH2, CH2CH2, and CH2 CH2 CH2; L1is selected from the group consisting of a covalent bond and (CH2)n; n is 1-5; R1 is selected from the group consisting of (a), (b), (c), (d), (e), (f), (g), (h), (i), (j), (k), and (l); R2is selected from the group consisting of hydrogen, alkoxycarbonyl, alkyl, aminoalkyl, aminocarbonylalkyl, benzyloxycarbonyl, cyanoalkyl, dihydro-3-pyridinylcarbonyl, hydroxy, hydroxyalkyl, phenoxycarbonyl, and-NH2; are useful for controlling synaptic transmission in mammal.

Diazabicyclic CNS active agents

Compounds of formula I: or pharmaceutically acceptable salts thereof, are useful for controlling synaptic transmission in mammals.