286957-61-7

Basic information

• Product Name: 2,3-[13C₂]-1,2-diphenylpropan-2-ol
• CAS NO: 286957-61-7
• Molecular Weight: 214.269
• Mol File: 286957-61-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,3-[13C₂]-1,2-diphenylpropan-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-[13C₂]-1,2-diphenylpropan-2-ol(286957-61-7)
• EPA Substance Registry System: 2,3-[13C₂]-1,2-diphenylpropan-2-ol(286957-61-7)

Safety Data

• Hazardous Substances Data: 286957-61-7(Hazardous Substances Data)

Upstream product

• 1589-82-8 phenylmagnesium bromide 
• 190314-15-9 acetophenone-α,β-(13)C2 

Downstream Products

• 286957-65-1 N-{[2,3-13C₂]1,2-diphenylprop-2-yl}formamide 
• 286957-71-9 2-{N-t-butoxycarbonylamino}-N-{[2,3-13C₂]-1,2-diphenylprop-2-yl}acetamide 
• 286957-68-4 [2,3-13C₂]-1,2-diphenylprop-2-ylamine 

Relevant articles and documents

Preparation of remacemide hydrochloride labelled with carbon-14, carbon-13, deuterium and tritium

The anti-epileptic agent remacemide hydrochloride has been prepared labelled with 14C, from [carbonyl-14C]acetophenone, and with 13C from [13C6]benzene, [1,2-13C]acetyl chloride and [1-13C]glycine. [2-3H]Glycine was utilised to prepare remacemide labelled with tritium at low specific activity. In addition other 2H- and high specific activity 3H-isotopomers of the drug, and of an active metabolite of the drug, were prepared by hydrogen isotope exchange methodology. The R-12C/S-14C and S-12C/R-14C pseudoracemic drugs were also prepared by a synthesis involving resolution of a 14C-labelled amine intermediate via fractional crystallisation of the dibenzoyltartrate salts.