2871-71-8Relevant academic research and scientific papers
Reduction of steroidal ketones with amine - Boranes
Leontjev,Vasiljeva,Pivnitsky
, p. 703 - 708 (2007/10/03)
Complexes of secondary amines with borane, R2NH·BH 3, surpass sodium borohydride as reducing agents for saturated and unsaturated steroidal 3-, 12-, 17-, and 20-ketones as regards chemo- and regioselectivity and mildness of the reaction conditions. In the case of 12-ketones, stereoselectivity is also improved.
Anti-inflammatory carboxy pregnane derivatives
-
, (2008/06/13)
Compounds of the formula: STR1 wherein one X is COOR, CH2 COOR, CH(COOR)2, CONHR, CH2 CONHR, or CN remaining X's are H, F, CH3, OH, COOR, CH2 COOR, CH(COOR)2, CONHR, CH2 CONHR, or CN; Y is STR2 R is H, alkyl of 1-5 carbon atoms, or benzyl; R1 is CH2 OR3, COOR, or CONHR; R2 is H, OR3, or BR; R3 is H, COR4, or tetrahydropyranyl; R4 is alkyl of 1-5 carbon atoms or benzyl; R5 is H or COR4 ; represents a single or double bond; represents α-position, β-position, or a mixture of α- and β-positions; and --- represents α-position; and methods for preparing the same.
