287101-20-6Relevant academic research and scientific papers
A radical cyclization route to pyrrolidines based on conjugate addition to electron deficient phenylselenenylalkenes
Berlin, Stefan,Engman, Lars
, p. 3701 - 3704 (2007/10/03)
α-Phenylselenenyl-α,β-unsaturated esters, amides, ketones, nitriles and sulfones were prepared by zinc chloride promoted chloroselenation/dehydrochlorination of the corresponding α,β-unsaturated compounds. After Michael addition of allyl or propargylamine and triethylborane initiated reductive radical cyclization in the presence of tris(trimethylsilyl)silane, pyrrolidine and dihydropyrrole derivatives, respectively, were obtained. (C) 2000 Elsevier Science Ltd.
