287108-63-8

Basic information

• Product Name: 5-bromo-3-methyl-2-[methyl-(4-pent-2-ynyloxy-benzenesulfonyl)-amino]-benzoic acid
• Synonyms: 5-bromo-3-methyl-2-[methyl-(4-pent-2-ynyloxy-benzenesulfonyl)-amino]-benzoic acid
• CAS NO: 287108-63-8
• Molecular Weight: 466.352
• Mol File: 287108-63-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 5-bromo-3-methyl-2-[methyl-(4-pent-2-ynyloxy-benzenesulfonyl)-amino]-benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 5-bromo-3-methyl-2-[methyl-(4-pent-2-ynyloxy-benzenesulfonyl)-amino]-benzoic acid(287108-63-8)
• EPA Substance Registry System: 5-bromo-3-methyl-2-[methyl-(4-pent-2-ynyloxy-benzenesulfonyl)-amino]-benzoic acid(287108-63-8)

Safety Data

• Hazardous Substances Data: 287108-63-8(Hazardous Substances Data)

Upstream product

• 6261-22-9 pent-2-yn-1-ol 
• 287108-60-5 5-bromo-2-[(4-hydroxy-benzenesulfonyl)-methyl-amino]-3-methyl-benzoic acid methyl ester 

Relevant articles and documents

ACETYLENIC ARYL SULFONAMIDE AND PHOSPHINIC ACID AMIDE HYDROXAMIC ACID TACE INHIBITORS

Hydroxamic acids having formula (B) wherein the variables are as defined herein, are useful in treating disease conditions mediated by TNF- alpha such as rheumatoid arthritis, osteoarthritis, sepsis, AIDS, ulcerative colitis, multiple sclerosis, Crohn's d

Acetylenic aryl sulfonamide and phosphinic acid amide hydroxamic acid TACE inhibitors

Hydroxamic acids having the formula are useful in treating disease conditions mediated by TNF-α, such as rheumatoid arthritis, osteoarthritis, sepsis, AIDS, ulcerative colitis, multiple sclerosis, Crohn's disease and degenerative cartilage loss.