28719-01-9 Usage
Indole derivative
The compound belongs to the class of indole derivatives, which are known for their diverse biological activities.
Nitrile group
The presence of a nitrile group (-C≡N) gives the compound unique chemical and physical properties.
Cyano-substituted phenyl ring
The presence of a cyano group (-CN) on a phenyl ring contributes to the compound's unique properties.
Building block in organic synthesis
The compound is often utilized as a building block in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds due to its structural versatility and potential for diverse functionalization.
Valuable tool in chemical research and development
The compound is commonly used in organic synthesis and medicinal chemistry, making it a valuable tool in these fields.
Check Digit Verification of cas no
The CAS Registry Mumber 28719-01-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,8,7,1 and 9 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 28719-01:
(7*2)+(6*8)+(5*7)+(4*1)+(3*9)+(2*0)+(1*1)=129
129 % 10 = 9
So 28719-01-9 is a valid CAS Registry Number.
28719-01-9Relevant academic research and scientific papers
PROCESSES FOR PREPARING INDOLES
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Paragraph 00101, (2013/07/05)
Methods for the synthesis of an indole in provided. Methods comprise oxidizing a N-aryl imine in the presence of a palladium-based catalyst, an oxidant, and a solvent.
Amidine derived inhibitors of acid-sensing ion channel-3 (ASIC3)
Kuduk, Scott D.,Chang, Ronald K.,Wai, Jenny M.-C.,Di Marco, Christina N.,Cofre, Victoria,DiPardo, Robert M.,Cook, Sean P.,Cato, Matthew J.,Jovanovska, Aneta,Urban, Mark O.,Leitl, Michael,Spencer, Robert H.,Kane, Stefanie A.,Hartman, George D.,Bilodeau, Mark T.
scheme or table, p. 4059 - 4063 (2010/04/05)
A series of indole amidines modified at the 2-position of the indole ring were evaluated as inhibitors of Acid-Sensing Ion Channel-3 (ASIC3), a novel target for the treatment of chronic pain.
