287203-80-9

Upstream product

• 127753-95-1 ethyl 2,3-O-isopropylidene-1-thio-α-L-rhamnopyranoside 
• 149707-75-5 2,3,4,6-tetra-O-benzoyl-D-glucopyranosyl trichloroacetimidate 

Downstream Products

• 255894-72-5 Diosgenyl 2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl-(1->4)-2,3-O-isopropylidene-α-L-rhamnopyranosyl-(1->4)-2,3-di-O-acetyl-6-O-benzoyl-β-D-glucopyranoside 
• 255894-70-3 Diosgenyl 2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl-(1->4)-2,3-O-isopropylidene-α-L-rhamnopyranosyl-(1->4)-[2,3,4-tri-O-acetyl-α-L-rhamnopyranosyl-(1->2)]-6-O-benzoyl-3-O-pivaloyl-β-D-glucopyranoside 

Relevant academic research and scientific papers

Synthesis of a group of diosgenyl saponins with combined use of glycosyl trichloroacetimidate and thioglycoside donors

With the combined use of glycosyl trichloroacetimidates and thioglycosides, a group of natural diosgenyl saponins (1-6) are efficiently synthesized, in either a stepwise or a 'one-pot' manner. The trichloroacetimidate is employed as an efficient temporary hydroxy protecting group in glycosylation with the glycosyl trichloroacetimidate. The intermolecular alkylthio-group transfer is demonstrated to be a common side-reaction during glycosylation with thioglycosides. The Royal Society of Chemistry 2000.