28747-20-8 Usage
Chemical Properties
White Solid
Uses
Different sources of media describe the Uses of 28747-20-8 differently. You can refer to the following data:
1. A glutathione derivative as inhibitor of glutathione S-transferase.
2. A glutathione derivative as inhibitor of glutathione S-transferase
Check Digit Verification of cas no
The CAS Registry Mumber 28747-20-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,8,7,4 and 7 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 28747-20:
(7*2)+(6*8)+(5*7)+(4*4)+(3*7)+(2*2)+(1*0)=138
138 % 10 = 8
So 28747-20-8 is a valid CAS Registry Number.
InChI:InChI=1/C12H21N3O7S/c13-7(12(21)22)1-2-9(17)15(5-10(18)19)11(20)8(14)6-23-4-3-16/h7-8,16H,1-6,13-14H2,(H,18,19)(H,21,22)/t7-,8-/m0/s1
28747-20-8Relevant articles and documents
Molecular modeling, synthesis, and preliminary biological evaluation of glutathione-S-transferase inhibitors as potential therapeutic agents
Procopio, Antonio,Alcaro, Stefano,Cundari, Sante,De Nino, Antonio,Ortuso, Francesco,Sacchetta, Paolo,Pennelli, Alfonso,Sindona, Giovanni
, p. 6084 - 6089 (2007/10/03)
Changes in the GSH/GST system have been found to correlate with resistance to anticancer alkylating agents, presumably through accelerated detoxification of these drugs since some GSTs have been shown to catalyze the conjugation of GSH to specific antineo