28748-92-7

Upstream product

• 635-46-1 1,2,3,4-tetrahydroisoquinoline 
• 100-47-0 benzonitrile 

Downstream Products

• 28748-77-8 1-phenyl-7,8-dihydro-3H,6H-[1,4]diazepino[6,7,1-ij]quinolin-4-one 
• 126149-70-0 3-amino-1-phenyl-7,8-dihydro-3H,6H-[1,4]diazepino[6,7,1-ij]quinolin-4-one 
• 126149-69-7 1-phenyl-7,8-dihydro-6H-[1,4]diazepino[6,7,1-ij]quinoline-3,4-dione 3-oxime 

Relevant academic research and scientific papers

Synthesis of 2-aminobenzophenones through acylation of anilines with α-oxocarboxylic acids assisted by: Tert -butyl nitrite

In this paper, a regioselective, efficient and convenient synthesis of 2-aminobenzophenones through acylation of anilines with α-oxocarboxylic acids assisted by tert-butyl nitrite is presented. Interestingly, tert-butyl nitrite acts as not only an efficient and mild nitrosation reagent, but also a sustainable oxidant required in the Pd(ii)-catalyzed decarboxylative acylation. Meanwhile, the NO unit turned out to be an easily introduced and readily removable directing group for the regioselective acylation.

NOVEL LIGAND COMPOUND AND TRANSITION METAL COMPOUND COMPRISING THE SAME

The present invention relates to a novel ligand compound and a transition metal compound containing the same. The novel ligand compound and the transition metal compound containing the same according to the present invention can be used as a polymerizatio

METHOD OF PREPARING LIGAND COMPOUND AND TRANSITION METAL COMPOUND

The present invention relates to a method of preparing a ligand compound and a transition metal compound comprising the same. An olefin based polymer with excellent material properties can be obtained using the transition metal compound obtained by said m

Synthesis and structure-activity relationships of 4-oxo-1-phenyl- 3,4,6,7-tetrahydro-[1,4]diazepino[6,7,1-hi]indoles: Novel PDE4 inhibitors

A novel series of benzodiazepine derivatives have been discovered as inhibitors of PDE4 enzymes. We have found that our compounds are selective versus other PDE enzymes, and that the activity can be modulated by specific structural modifications. One compound exhibited a strong eosinophilic infiltration inhibiting action on sensitized Brown-Norway rats (compound 9, 5.1 mg/kg p.o.), moreover this compound is not emetic at 3 mg/kg i.v.