28751-26-0

Basic information

• Product Name: DIETHYL 2-(3,4-DICHLOROPHENYL)MALONATE
• Synonyms: DIETHYL 2-(3,4-DICHLOROPHENYL)MALONATE;RARECHEM AL BI 1249;Diethyl (3,4-dichlorophenyl)malonate, 95%
• CAS NO: 28751-26-0
• Molecular Formula: C₁₃H₁₄Cl₂O₄
• Molecular Weight: 305.15
• Mol File: 28751-26-0.mol

Chemical Properties

• Boiling Point: 359.1°Cat760mmHg
• Flash Point: 133.8°C
• Appearance: /
• Density: 1.29g/cm³
• Vapor Pressure: 2.44E-05mmHg at 25°C
• Refractive Index: 1.5105
• CAS DataBase Reference: DIETHYL 2-(3,4-DICHLOROPHENYL)MALONATE(CAS DataBase Reference)
• NIST Chemistry Reference: DIETHYL 2-(3,4-DICHLOROPHENYL)MALONATE(28751-26-0)
• EPA Substance Registry System: DIETHYL 2-(3,4-DICHLOROPHENYL)MALONATE(28751-26-0)

Safety Data

• Hazardous Substances Data: 28751-26-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
DIETHYL 2-(3,4-DICHLOROPHENYL)MALONATE is used as a key intermediate in the synthesis of various pharmaceuticals. Its unique structure allows for the development of new drugs with potential therapeutic benefits.
Used in Agrochemical Industry:
In the agrochemical sector, DIETHYL 2-(3,4-DICHLOROPHENYL)MALONATE is utilized as an intermediate for the production of agrochemicals. Its insecticidal and acaricidal properties make it a valuable component in the creation of effective pest control agents.
Used in Fine Chemicals Industry:
DIETHYL 2-(3,4-DICHLOROPHENYL)MALONATE is also employed in the synthesis of other fine chemicals, where its specific functional groups and structural features are leveraged to produce high-quality specialty chemicals for various applications.
Used in Research Applications:
DIETHYL 2-(3,4-DICHLOROPHENYL)MALONATE has been studied for its potential as a fluorescent probe for detecting reactive oxygen species in biological systems. This application highlights its utility in scientific research and the development of diagnostic tools.
Safety Considerations:
It is crucial to handle DIETHYL 2-(3,4-DICHLOROPHENYL)MALONATE with care due to its potential hazards. Ingestion, inhalation, or contact with skin and eyes can cause harm, necessitating proper safety measures during its use and storage.

InChI:InChI=1/C13H14Cl2O4/c1-3-18-12(16)11(13(17)19-4-2)8-5-6-9(14)10(15)7-8/h5-7,11H,3-4H2,1-2H3

Upstream product

• 6725-45-7 ethyl 3,4-dichlorophenylacetate 
• 95-92-1 oxalic acid diethyl ester 
• 105-58-8 Diethyl carbonate 

Downstream Products

• 29246-13-7 (3,4-Dichlor-phenyl)-fluor-malonsaeure-diaethylester 
• 1363142-66-8 2-{8-(3,4-dichlorophenyl)-3-[3-methoxy-4-(2-methyl-1,3-oxazol-5-yl)phenyl]-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridin-8-yl}propan-2-ol 
• 29229-88-7 3,4-Dichlor-α-fluor-phenylessigsaeure-aethylester 
• 696575-81-2 (3,4-Dichlor-phenyl)-fluor-malonsaeure 
• 29229-91-2 α-(3,4-Dichlorophenyl)-α-fluoressigsaeure 

Relevant articles and documents

Discovery of novel 5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridine derivatives as γ-secretase modulators (Part 2)

γ-Secretase modulators (GSMs), which lower pathogenic amyloid beta (Aβ) without affecting the production of total Aβ or Notch signal, have emerged as a potential therapeutic agent for Alzheimer's disease (AD). A novel series of 5,6,7,8-tetrahydro[1,2,4]tr