28753-34-6 Usage
Uses
Used in Pharmaceutical Research:
2,4,6,8-tetra(piperidin-1-yl)pyrimido[5,4-d]pyrimidine is used as a research compound for exploring its potential biological activities and pharmacological properties. The presence of piperidine groups in its structure makes it a promising candidate for the development of new drugs with various therapeutic applications.
Used in Drug Development:
As a member of the pyrimido[5,4-d]pyrimidine family, 2,4,6,8-tetra(piperidin-1-yl)pyrimido[5,4-d]pyrimidine is used as a starting point for the design and synthesis of new drug molecules. Its unique structure and potential biological activities can be leveraged to develop novel therapeutic agents with improved efficacy and selectivity.
Used in Medicinal Chemistry:
2,4,6,8-tetra(piperidin-1-yl)pyrimido[5,4-d]pyrimidine serves as a valuable tool in medicinal chemistry for the study of structure-activity relationships and the optimization of drug candidates. Its complex structure and the presence of piperidine groups allow for systematic modifications to investigate the impact of structural variations on biological activity and pharmacokinetic properties.
Check Digit Verification of cas no
The CAS Registry Mumber 28753-34-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,8,7,5 and 3 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 28753-34:
(7*2)+(6*8)+(5*7)+(4*5)+(3*3)+(2*3)+(1*4)=136
136 % 10 = 6
So 28753-34-6 is a valid CAS Registry Number.
28753-34-6Relevant academic research and scientific papers
Structure-activity relationships of pyrimido-pyrimidine series of 5-lipoxygenase inhibitors
Basha, Anwer,Ratajczyk, James D.,Dyer, Richard D.,Young, Patrick,Carter, George W.,Brooks, Clint D.W.
, p. 61 - 67 (2007/10/03)
A series of pyrimido-pyrimidine compounds were synthesized and a SAR study was conducted for 5-LO inhibition using a broken cell preparation from RBL-1 cells. In this series compound 21 was found to be a potent 5-LO inhibitor in vitro.
