287721-05-5

Basic information

• Product Name: 4-[phenyl(endo-8-methyl-8-azabicyclo[3.2.1]octan-3-yl)amino]benzoic acid
• Synonyms: 4-[phenyl(endo-8-methyl-8-azabicyclo[3.2.1]octan-3-yl)amino]benzoic acid
• CAS NO: 287721-05-5
• Molecular Weight: 336.434
• Mol File: 287721-05-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-[phenyl(endo-8-methyl-8-azabicyclo[3.2.1]octan-3-yl)amino]benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[phenyl(endo-8-methyl-8-azabicyclo[3.2.1]octan-3-yl)amino]benzoic acid(287721-05-5)
• EPA Substance Registry System: 4-[phenyl(endo-8-methyl-8-azabicyclo[3.2.1]octan-3-yl)amino]benzoic acid(287721-05-5)

Safety Data

• Hazardous Substances Data: 287721-05-5(Hazardous Substances Data)

Upstream product

• 62-53-3 aniline 
• 63930-13-2 endo-3-(N-phenylamino)tropane 
• 532-24-1 tropinone 
• 287721-06-6 1,1-dimethylethyl 4-[phenyl(endo-8-methyl-8-azabicyclo[3.2.1]octan-3-yl)amino]benzoate 

Downstream Products

• 287720-97-2 N-ethyl-N-methyl-4-[(8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl)-phenyl-amino]-benzamide 
• 287720-75-6 N,N-diethyl-4-[phenyl(endo-8-azabicyclo[3.2.1]octan-3-yl)amino]benzamide 
• 287720-73-4 N,N-diethyl-4-[(8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl)-phenyl-amino]-benzamide 
• 287721-02-2 N,N-dimethyl-4-[(8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl)-phenyl-amino]-benzamide 
• 287720-98-3 4-[(8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl)-phenyl-amino]-N,N-dipropyl-benzamide 

Relevant articles and documents

Synthesis and binding affinities of 4-diarylaminotropanes, a new class of delta opioid agonists

A series of 4-diarylaminotropanes has been prepared. Both endo and exo diastereomeric forms bound to the delta opioid receptor but the endo isomers were more potent and selective versus the μ opioid receptor than the exo isomers. The most potent delta opioid agonist (14) exhibited a delta opioid K(i) of 0.2 nM and was 860-fold selective over mu. (C) 2000 Elsevier Science Ltd. All rights reserved.