28773-97-9Relevant academic research and scientific papers
Efficient Synthesis of Tetraacetylglycoluril in the Presence of Phosphorus-Containing Catalysts
Bakibaev,Panshina, S. Yu.,Hoang,Kurgachev,Ukhov,Malkov,Zhumanov
, p. 58 - 63 (2021/03/03)
Abstract: The effect of phosphorus-containing catalysts, namely phosphorous acid, phosphoric acid, diethyl hydrogen phosphite, and 1-hydroxyethane-1,1-diyldiphosphonic acid (HEDP), in the synthesis of tetraacetylglycoluril by acylation of glycoluril with acetic anhydride at 140°C has been studied. The use of 4 equiv of phosphorous or phosphoric acid with respect to glycoluril has been found to be the most appropriate for achieving the maximum yield (95–98%), and specific effect of HEDP leads to N-acetylation–deacetylation of substrates. The positive effect of phosphorus acids on the formation of tetraacetylglycoluril may be related to not only their catalytic action but also the ability to solubilize the substrate.
1,6-Dibenzylglycoluril for synthesis of deprotected glycoluril dimer
Stancl, Marek,Khan, Muhammad S.A.,Sindelar, Vladimir
experimental part, p. 8937 - 8941 (2011/12/01)
1,6-Dibenzylglycoluril is not accessible via classical condensation reaction between substituted urea and glyoxal. In this paper 1,6-dibenzylglycoluril was successfully prepared by alkylation of 1,6-diacetylglycoluril with benzylbromide for the first time. 1,6-Dibenzylglycoluril reacted with formaldehyde to give tetrabenzylglycoluril dimer. Deprotection of this dimer and the previously reported o-xylyleneglycoluril dimer was achieved by dissolving metal reduction, whereas propyleneglycoluril dimer was deprotected by action of potassium persulfate.
Methodes de preparation de derives nitres et nitroacetyles du glycolurile (I)
Boileau, J.,Wimmer, E.,Carail, M.,Gallo, R.
, p. 465 - 469 (2007/10/02)
A procedure for preparing nitro and nitroacetyl derivatives of glycoluril is described, starting from tetraacetylglycoluril (TAGU).The method proceeds by nitrodeacetylation and (or) hydrolysis.New compounds have been prepared : mononitrodiacetylglycoluril (MONDAGU), dinitrodiacetylglycoluril (DINDAGU) and mononitroglycoluril (MONGU).A general synthetic scheme is proposed and discussed.Some properties of the new derivatives are presented.
