287933-70-4

Basic information

• Product Name: (3S)-4-phenylsulfonyl-2,3-dihydrofuran-3-methanol
• Synonyms: (3S)-4-phenylsulfonyl-2,3-dihydrofuran-3-methanol
• CAS NO: 287933-70-4
• Molecular Weight: 240.28
• Mol File: 287933-70-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (3S)-4-phenylsulfonyl-2,3-dihydrofuran-3-methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (3S)-4-phenylsulfonyl-2,3-dihydrofuran-3-methanol(287933-70-4)
• EPA Substance Registry System: (3S)-4-phenylsulfonyl-2,3-dihydrofuran-3-methanol(287933-70-4)

Safety Data

• Hazardous Substances Data: 287933-70-4(Hazardous Substances Data)

Upstream product

• 38238-75-4 (E)-2-chloroethenyl phenyl sulfone 
• 448896-27-3 (R)-2-((E)-(2-phenylsulfonyl)-ethenyloxymethyl)-oxirane 
• 287933-69-1 (S)-2-((E)-2-Benzenesulfonyl-vinyloxymethyl)-oxirane 

Downstream Products

• 287933-77-1 1-((1R,2R,3R)-tetrahydro-2-(1,1-dimethylethyldiphenyl)-silyloxy-3-(1,1-dimethylethyldiphenyl)-silyloxymethyl-1-furanyl)-4-(1,2,4-triazol-1-yl)-2(1H)-pyrimidinone 
• 448896-42-2 4-amino-1-((1R,2R,3R)-tetrahydro-2-(1,1-dimethylethyldiphenyl)-silyloxy-3-(1,1-dimethylethyldiphenyl)-silyloxymethyl-1-furanyl)-2(1H)-pyrimidinone 
• 448896-41-1 1-((1R,2R,3R)-tetrahydro-2-(1,1-dimethylethyldiphenyl)-silyloxy-3-(1,1-dimethylethyldiphenyl)-silyloxymethyl-1-furanyl)-2,4(1H,3H)-pyrimidinedione 
• 287933-80-6 6-N-benzoyl-9-((1R,2R,3S)-tetrahydro-2-acetoxy-3-(((4-methoxyphenyl)-diphenylmethoxy)-methyl)-1-furanyl)-9H-adenine 
• 287933-94-2 5-methyl-1-((1R,2R,3S)-tetrahydro-2-hydroxy-3-(((4-methoxyphenyl)-diphenylmethoxy)-methyl)-1-furanyl)-2,4(1H,3H)-pyrimidinedione 
• 287933-84-0 5-methyl-1-((1R,2S,3S)-tetrahydro-2-hydroxy-3-(((4-methoxyphenyl)-diphenylmethoxy)-methyl)-1-furanyl)-2,4(1H,3H)-pyrimidinedione 
• 287933-83-9 5-methyl-1-((1R,2R,3R)-tetrahydro-2-azido-3-(1,1-dimethylethyldiphenyl)-silyloxymethyl-1-furanyl)-2,4(1H,3H)-pyrimidinedione 
• 287933-97-5 2,2'-anhydro-5-methyl-1-((1R,2S,3S)-tetrahydro-2-hydroxy-3-(((4-methoxyphenyl)-diphenylmethoxy)-methyl)-1-furanyl)-2,4(1H,3H)-pyrimidinedione 
• 287933-75-9 5-methyl-1-((1R,2R,3R)-tetrahydro-2-hydroxy-3-(1,1-dimethylethyldiphenyl)-silyloxymethyl-1-furanyl)-2,4(1H,3H)-pyrimidinedione 
• 287933-76-0 1-((1R,2R,3R)-tetrahydro-2-hydroxy-3-(1,1-dimethylethyldiphenyl)-silyloxymethyl-1-furanyl)-2,4(1H,3H)-pyrimidinedione 
• 287933-82-8 2,2'-anhydro-5-methyl-1-((1R,2S,3R)-tetrahydro-2-hydroxy-3-(1,1-dimethylethyldiphenyl)-silyloxymethyl-1-furanyl)-2,4(1H,3H)-pyrimidinedione 
• 287933-87-3 5-methyl-1-((1R,2R,3S)-tetrahydro-3-benzoyloxymethyl-2-fluoro-1-furanyl)-2,4(1H,3H)-pyrimidinedione 
• 287933-85-1 5-methyl-1-((1R,2S,3S)-tetrahydro-2-hydroxy-3-benzoyloxymethyl-1-furanyl)-2,4(1H,3H)-pyrimidinedione 
• 19200-56-7 9-((1R,2R,3S)-tetrahydro-2-hydroxy-3-(hydroxymethyl)-1-furanyl)-9H-adenine 

Relevant articles and documents

Synthesis and biological activity of a series of methylene-expanded oxetanocin nucleoside analogues

A series of methylene-expanded oxetanocin nucleoside analogues, e.g. analogues of 2 and the known antiviral nucleosides AZT, FLT, and ddC (3) were prepared by a very direct route beginning with the readily available (S)-glycidol 4 and proceeding via the dihydrofuran-3-methanols 9a,b. Biological testing of these modified nucleosides indicates that they are non-cytotoxic compounds with generally weak antiviral activity. However, the guanosine analogue 2G showed pronounced activity vs. herpes simplex virus type 1 (HSV-1) in cell culture and was HSV-1-encoded thymidine kinase dependent. This compound is therefore an interesting new lead structure for the development of new anti-HSV agents.