287935-20-0

Upstream product

• 6097-21-8 2-(4-nitrophenyl)-2-oxoethyl thiocyanate 
• 62675-68-7 S-(triphenylmethyl)-L-cysteine methyl ester hydrochloride 
• 2799-07-7 S-trityl-L-cysteine 
• 76-83-5 trityl chloride 
• 99-81-0 4-Nitrophenacyl bromide 

Downstream Products

• 329015-89-6 2-Bromo-5-[dimethyl-(1,1,2-trimethyl-propyl)-silanyloxy]-3-methoxy-6-{(R)-2-methoxycarbonyl-2-[4-(4-nitro-phenyl)-thiazol-2-ylamino]-ethylsulfanylmethyl}-benzoic acid methyl ester 
• 329015-88-5 (R)-3-Mercapto-2-[4-(4-nitro-phenyl)-thiazol-2-ylamino]-propionic acid methyl ester 

Relevant academic research and scientific papers

seco-Cyclothialidines: New concise synthesis, inhibitory activity toward bacterial and human DNA topoisomerases, and antibacterial properties

seco-Cyclothialidines are a promising class of bacterial DNA gyrase B subunit inhibitors. A new seco-cyclothialidine derivative containing a dioxazine moiety, BAY 50-7952, was synthesized through a new concise pathway. One key step of the synthesis is the

Facile access to N-thiazolyl α-amino acids from α-bromo ketones and α-amino acids

N-Substituted 2-aminothiazoles are synthesized in a one-pot procedure using readily available α-bromo ketones and amines. This method is compatible with a wide range of functional groups and offers a facile and efficient access to the class of N-thiazolyl