287944-24-5Relevant articles and documents
Microbial transformation of 2-hydroxy and 2-acetoxy ketones with Geotrichum sp.
Wei, Zhi-Liang,Lin, Guo-Qiang,Li, Zu-Yi
, p. 1129 - 1137 (2000)
Biotransformation of a series of o-, m- and p-substituted α-hydroxy- and α-acetoxyphenylethanones 1a-h and 9a-g with Geotrichum sp. led to the corresponding 1,2-diols 2 and/or monoacetates 10 in moderate to excellent enantiomeric excesses. α-Hydroxy- and α-acetoxyphenylethanones and their m- and p-derivatives gave preponderantly the S-configuration products while in the case of the o-derivatives R-alcohol was provided as the major enantiomer. The results of stereoselectivity were discussed. (C) 2000 Elsevier Science Ltd.