287958-89-8 Usage
Uses
Used in Organic Chemistry:
2-cyano-2-methyl-1-cyclobutanone is used as a synthetic intermediate for the synthesis of various organic compounds. Its unique structure allows for versatile reactions and the formation of diverse chemical products.
Used in Pharmaceutical Industry:
2-cyano-2-methyl-1-cyclobutanone is used as a building block in the development of pharmaceuticals. Its ability to be incorporated into complex molecular structures makes it valuable in the creation of new drugs.
Used in Enzyme Research:
2-cyano-2-methyl-1-cyclobutanone is used as a strong and selective α-chymotrypsin inhibitor. This makes it a useful tool in enzyme research, helping scientists understand enzyme function and develop new drugs targeting specific enzymes.
Used in Drug Development:
2-cyano-2-methyl-1-cyclobutanone is used in drug development due to its potential therapeutic properties. Its ability to inhibit enzymes and its potential use in treating neurodegenerative diseases make it a promising candidate for further research and development.
Used in Neurodegenerative Disease Treatment:
2-cyano-2-methyl-1-cyclobutanone has been studied for its potential use in the treatment of neurodegenerative diseases. Its specific properties may offer new avenues for therapeutic intervention in conditions such as Alzheimer's and Parkinson's disease.
Check Digit Verification of cas no
The CAS Registry Mumber 287958-89-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,8,7,9,5 and 8 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 287958-89:
(8*2)+(7*8)+(6*7)+(5*9)+(4*5)+(3*8)+(2*8)+(1*9)=228
228 % 10 = 8
So 287958-89-8 is a valid CAS Registry Number.
287958-89-8Relevant academic research and scientific papers
Cycloaddition reactions of ketene diethyl acetal toward the synthesis of cyclobutene monomers
Kniep, Carina S.,Padias, Anne B.,Hall Jr.
, p. 4279 - 4288 (2007/10/03)
The [2+2]-cycloaddition reactions of ketene diethyl acetal with methyl acrylate and acrylonitrile were optimized. Highly efficient ketal cleavage to either 2-cyano-1-cyclobutanone or 2-methoxycarbonyl-1-cyclobutanone was achieved using formic acid. Among the numerous reduction methods attempted, only sodium cyanoborohydride in acidic medium led successfully to the corresponding alcohols, but isolation of the desired products was not achievable. We show that the anomalous cyclobutanone chemistry is due to the acidic α-proton and the electron-withdrawing substituent in the α-position. Substitution of the α-proton by a methyl group results in a turnaround back to textbook chemistry. (C) 2000 Elsevier Science Ltd.
