288-01-7Relevant academic research and scientific papers
Phospholes with functional substituents on the phosphorus and process for the preparation of phospholes
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, (2008/06/13)
The phospholes and P-functional phospholes correspond to the general formula: STR1 in which: R1 and R2 are identical or different and represent hydrogen or a lower alkyl group of C1 to C4 such as a methyl group, and R3 represents an aryl group (such as --C6 H5) or a substituted aryl group (such as --CH2 C6 H5) or an alkyl group (such as --CH3, --C2 H5, --C3 H7 to C12 H25) or a --(CH2)n Z group where Z denotes a function of the --COO-alkyl type (such as --COOC2 H5), --CH, --CO-aryl (such as --COC6 H5), --CO-alkyl (such as --COCH3) or --OH and n≥1. At least one alkyl- or arylhalogeno phosphine is reacted with a butadiene whose carbons in the 2 and/ or 3 positions carry possibly a lower alkyl substituent, the cyclic adduct resulting from this reaction is then subjected to the action of a tertiary amine selected from among those having a pKa comprised between 5 and 11, then the product obtained is functionalized if the corresponding P-functional product is desired. Some of the phospholes thus produced are novel, particularly those of the above formula wherein R3 =--(CH2)n Z such as above defined with n≠2 for Z=CN.
