288-16-4 Usage
Description
Isothiazole is a heterocyclic compound featuring a five-membered ring with one nitrogen and one sulfur atom. It is known for its unique chemical properties and serves as a valuable intermediate in the synthesis of various biologically active compounds.
Uses
Used in Pharmaceutical Industry:
Isothiazole is used as a building block for the synthesis of pharmaceutical drugs, such as ziprasidone (Z485000) and perospirone (P288900), due to its ability to contribute to the development of complex compounds with significant biological activity. This makes it a crucial component in the creation of medications that address various health conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 288-16-4 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 2,8 and 8 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 288-16:
(5*2)+(4*8)+(3*8)+(2*1)+(1*6)=74
74 % 10 = 4
So 288-16-4 is a valid CAS Registry Number.
InChI:InChI=1/C3H3NS/c1-2-4-5-3-1/h1-3H
288-16-4Relevant articles and documents
PHOTOLYSIS OF BROMOTHIAZOLES IN HYDROGEN-DONATING SOLVENTS. A THEORETICAL STUDY AND PHYSICAL PROPERTIES OF BROMOTHIAZOLES
Parkanyi, Cyril,Vernin, Gaston,Zamkostian, Rose-Marie,Metzger, Jacques
, p. 1077 - 1089 (2007/10/02)
Uv irradiation of bromothiazoles in various organic solvents (methanol, ether, cyclohexane) produces thiazole and the isomeric isothiazole as the main reaction products.The reactivity of monobromothiazoles in this reaction decreases in the order: 2-bromothiazole > 5-bromothiazole >> 4-bromothiazole.The PPP (LCI-SCF-MO) calculations of bromothiazoles were used to interpret and discuss their various properties.The uv, NMR, and mass spectra of bromothiazoles were measured.