288068-75-7Relevant academic research and scientific papers
An efficient synthesis of chiral homophenylalanine derivatives via enantioselective hydrogenation
Li, Xingshu,Yeung, Chi-Hung,Chan, Albert S. C.,Lee, Dong-Sheng,Yang, Teng-Kuei
, p. 3863 - 3867 (2007/10/03)
Chiral homophenylalanine derivatives were synthesized via enantioselective hydrogenation of 5a and 5b catalyzed by rhodium complexes bearing chiral phosphine and phosphinite legands. Enantiomeric excesses up to 96.2% were achieved when S-spiroOP(S-1) was used as a chiral ligand under 500 psi of H2 pressure in acetone.
