288083-18-1

Basic information

• Product Name: C₉H₈N₃S^(1-)*Na⁽¹⁺⁾
• CAS NO: 288083-18-1
• Molecular Weight: 213.238
• Mol File: 288083-18-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₉H₈N₃S^(1-)*Na⁽¹⁺⁾(CAS DataBase Reference)
• NIST Chemistry Reference: C₉H₈N₃S^(1-)*Na⁽¹⁺⁾(288083-18-1)
• EPA Substance Registry System: C₉H₈N₃S^(1-)*Na⁽¹⁺⁾(288083-18-1)

Safety Data

• Hazardous Substances Data: 288083-18-1(Hazardous Substances Data)

Upstream product

• 19981-17-0 sodium cyanamide 
• 614-69-7 2-tolyl isothiocyanate 

Downstream Products

• 1001183-82-9 C₁₉H₂₁N₅ 
• 1010743-68-6 C₁₅H₂₁N₅ 
• 1010743-66-4 C₁₇H₂₅N₅ 

Relevant articles and documents

Synthesis and in vitro activity of N′-cyano-4-(2-phenylacetyl)-N-o-tolylpiperazine-1-carboximidamide P2X7 antagonists

A novel series of cyanoguanidine-piperazine P2X7 antagonists was designed based upon the structure of A-740003. Structure-activity relationship (SAR) studies focused on the piperazine moiety and the right hand side substitution. Compounds were assayed for activity at human and rat P2X7 receptors and compound 29 was found to possess potent activity (IC50 = 30-60 nM) at both species.