288104-79-0 Usage
General Description
Surinabant is a potent and selective antagonist for the cannabinoid-1 receptor, which plays a critical role in regulating appetite and body weight. It was developed as a potential treatment for obesity and related metabolic disorders by blocking the action of the cannabinoid system, which is responsible for promoting hunger and increasing energy storage. However, clinical development of surinabant was discontinued due to the concern of potential psychiatric side effects, such as depression and anxiety. Despite its promising initial effects on weight loss and improvements in metabolic parameters, the safety profile of surinabant raised significant doubts, leading to its discontinuation in clinical trials and further development.
Check Digit Verification of cas no
The CAS Registry Mumber 288104-79-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,8,8,1,0 and 4 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 288104-79:
(8*2)+(7*8)+(6*8)+(5*1)+(4*0)+(3*4)+(2*7)+(1*9)=160
160 % 10 = 0
So 288104-79-0 is a valid CAS Registry Number.
InChI:InChI=1/C23H23BrCl2N4O/c1-2-18-21(23(31)28-29-12-4-3-5-13-29)27-30(20-11-10-17(25)14-19(20)26)22(18)15-6-8-16(24)9-7-15/h6-11,14H,2-5,12-13H2,1H3,(H,28,31)
288104-79-0Relevant articles and documents
PROCESS FOR PREPARATION OF PYRAZOLE DERIVATIVES
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, (2008/12/08)
A process for preparation of Pyrazole derivatives adapted for one pot reaction involving the use of a pyclizing agent and involving the step of amidation in the presence of a catalyst. The steps for isolation and purification of found Pyrazole derivatives are also disclosed.
