6-thiopurine-5'-deoxyriboside, also known as 6-thioguanine deoxyriboside or 6-TG, is a chemical compound derived from the purine family. It is a nucleoside analog, which means it is structurally similar to a natural nucleoside but with a modified base or sugar component. 6-TG is used as a prodrug in the treatment of certain autoimmune diseases and cancer, as it is converted into the active drug 6-thioguanine within the body. This conversion is facilitated by the enzyme purine nucleoside phosphorylase. The compound is particularly effective in treating conditions such as psoriasis and rheumatoid arthritis, as well as certain leukemias. It works by inhibiting DNA synthesis and RNA function, thereby disrupting the replication and transcription processes in cells, which is crucial for the growth and survival of cancerous cells and the overactive immune response in autoimmune diseases.
The CAS Registry Mumber 2882-09-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,8,8 and 2 respectively; the second part has 2 digits, 0 and 9 respectively. Calculate Digit Verification of CAS Registry Number 2882-09: (6*2)+(5*8)+(4*8)+(3*2)+(2*0)+(1*9)=99 99 % 10 = 9 So 2882-09-9 is a valid CAS Registry Number.