288268-32-6

Basic information

• Product Name: bis-(2,4-tert-butoxycarbonyloxy)-benzaldehyde
• Synonyms: bis-(2,4-tert-butoxycarbonyloxy)-benzaldehyde
• CAS NO: 288268-32-6
• Molecular Weight: 338.357
• Mol File: 288268-32-6.mol

Chemical Properties

• CAS DataBase Reference: bis-(2,4-tert-butoxycarbonyloxy)-benzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: bis-(2,4-tert-butoxycarbonyloxy)-benzaldehyde(288268-32-6)
• EPA Substance Registry System: bis-(2,4-tert-butoxycarbonyloxy)-benzaldehyde(288268-32-6)

Safety Data

• Hazardous Substances Data: 288268-32-6(Hazardous Substances Data)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 95-01-2 2,4-Dihydroxybenzaldehyde 

Downstream Products

• 950487-13-5 tert-butyl 3-hydroxy-4-(2-nitro-3-(triisopropylsilyloxy)propyl)phenyl carbonate 
• 950487-14-6 methyl 3-(4-(tert-butoxycarbonyloxy)-2-hydroxyphenyl)-2-nitropropanoate 
• 288268-34-8 2-ethyl-5-tert-butoxycarbonyloxy-phenol 
• 288268-46-2 1-(hydroxy-methyl)-2,5-di-tert-butoxycarbonyloxy-benzene 

Relevant articles and documents

INHIBITORS OF LEUKOTRIENE PRODUCTION

The present invention relates to aryl pyrazoles, and pharmaceutically acceptable salts thereof. The aryl pyrazoles of the present invention are useful as inhibitors of leukotriene A4 hydrolase (LTA4H) and treating LTA4H related disorders. The present invention also relates to pharmaceutical compositions comprising the aryl pyrazoles of the present invention, methods of using these compounds in the treatment of various diseases and disorders, and processes for preparing these compounds.

HIF-1α inhibitors: Synthesis and biological evaluation of novel moracin O and P analogues

The natural products moracins O and P exhibited potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1), which is a key mediator during adaptation of cancer cells to tumour hypoxia. Systematic variations of the structures of benzofuran type moracins were made and structure-activity relationship analysis showed the importance of the 2-arylbenzofuran ring and the (R)-configuration of the core scaffold. Further evaluation of the representative compound 5 showed its inhibitory effect on HIF-1α protein accumulation and target gene expression under hypoxia.

Total synthesis of (+)-rishirilide B: Development and application of general processes for enantioselective oxidative dearomatization of resorcinol derivatives

A concise synthesis of (+)-rishirilide B (2) is described. This is the first synthesis to be reported for the (+)-enantiomer of rishirilide B (2) as found in nature. The strategy accentuates the valuable combination of a method for oquinone methide coupli

Strategies for the preparation of differentially protected ortho-prenylated phenols

A new process for ortho-prenylation of phenols is presented within the context of known methods. All of the processes are briefly assessed with regards to the substitution patterns and accompanying functional groups tolerated by each strategy. The conclus

A mild anionic method for generating o-quinone methides: Facile preparations of ortho-functionalized phenols

A low-temperature method for generating o-quinone methides is described which permits facile introduction of assorted R substituents onto the aryl ring system at low temperature. The method is useful for the efficient preparation of ortho-ring-alkylated phenols.