288270-25-7Relevant academic research and scientific papers
Total synthesis of pyrrolizidines 223H', 239K', 265H', and 267H' found in madagascan frogs (Mantella) and their affinities for nicotinic acetylcholine receptor
Takahata, Hiroki,Takahashi, Seiki,Azer, Nehad,Eldefrawi, Amira T.,Eldefrawi, Mohyee E.
, p. 1293 - 1295 (2007/10/03)
The total synthesis of pyrrolizidines 223H', 239K', 265H' and 267H' has been achieved starting from 1,5-hexadiene via a common synthetic intermediate 5. The affinity of 1-4 for nicotinic acetylcholine receptor was evaluated. (C) 2000 Elsevier Science Ltd. All rights reserved.
