288317-39-5Relevant academic research and scientific papers
Spontaneous aldol and Michael additions of simple enoxytrimethylsilanes in DMSO
Génisson, Yves,Gorrichon, Liliane
, p. 4881 - 4884 (2007/10/03)
Activation of simple trimethylsilyl ketene acetals by dipolar aprotic solvents has been evidenced, allowing efficient solvent assisted aldol and Michael additions under extremely simple, mild and metal free conditions. (C) 2000 Elsevier Science Ltd.
Combined Use of Diphenyltin Sulfide or Lawesson's Reagent and Silver Perchlorate as Effective Catalyst Systems in Aldol Reaction
Mukaiyama, Teruaki,Saito, Katsuyuki,Kitagawa, Hideo,Shimomura, Naoyuki
, p. 789 - 792 (2007/10/02)
Catalytic aldol reactions of several aldehydes with trimethylsilyl enol ethers are effectively performed by combined use of diphenyltin sulfide (Ph2Sn=S) and silver perchlorate (AgClO4) or Lawesson's reagent (2,4-bis(4-methoxyphenyl)-1,3-dithia-2,4-diphos
Cobalt(II) Catalyzed Coupling Reaction of α,β-Unsaturated Compounds with Aldehydes by the Use of Phenylsilane. New Method for Preparation of β-Hydroxy Nitriles, Amides, and Esters
Isayama, Shigeru,Mukaiyama, Teruaki
, p. 2005 - 2008 (2007/10/02)
A new crossed coupling reaction of α,β-unsaturated nitriles with aldehydes was performed by using phenylsilane and a catalytic amount of bis(1,3-diketonato)cobalt(II) to give β-siloxy nitriles in good yields.Similarly, α,β-unsaturated amides and esters also reacted under the same conditions to afford β-siloxy amides or esters.The present reaction provides a new and facile method for preparation of β-hydroxy nitriles, amides, and esters.
