288395-73-3

Upstream product

• 7797-83-3 2H-benzo[d]1,3-dioxolane-4-carbaldehyde 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 288395-72-2 4-(1-Ethoxy-ethoxy)-benzo[1,3]dioxole-5-carboxylic acid [(1R,5R,6R)-5-(tert-butyl-dimethyl-silanyloxy)-7-oxa-bicyclo[4.1.0]hept-3-en-3-yl]-amide 
• 288395-71-1 (-)-5-(tert-butyl-dimethylsilanyloxy)-7-oxa-bicyclo[4.1.0]hept-3-ene-3-carboxylic acid 
• 288395-83-5 5-butyryloxy-7-oxa-bicyclo[4.1.0]hept-3-ene-3-carboxylic acid methyl ester 
• 192210-65-4 5-bromo-4-(1-ethoxyethoxy)-2H-benzo[d]1,3-dioxolane 
• 106861-68-1 (1R,5R,6R)-5-(tert-Butyl-dimethyl-silanyloxy)-7-oxa-bicyclo[4.1.0]hept-3-ene-3-carboxylic acid methyl ester 
• 106861-61-4 (+)-methyl (1β,2α,6β)-2-hydroxy-7-oxabicyclo<4,1,0>hept-3-ene-4-carboxylate 
• 200182-30-5 methyl 2-hydroxy-7-oxabicyclo[4.1.0]hept-3-ene-4-carboxylate 
• 82299-36-3 bromo-5 hydroxy-4 benzodioxole-1,3 
• 106861-60-3 (-)-methyl (1β,2β,6β)-2-hydroxy-7-oxabicyclo<4,1,0>hept-3-ene-4-carboxylate 
• 69393-72-2 2H-benzo[d][1,3]dioxolan-4-ol 
• 54162-19-5 2,4-Cyclohexadien-1-carbonsaeure-methylester 
• 6493-77-2 methyl cyclohex-3-ene-1-carboxylate 

Relevant academic research and scientific papers

Studies on the narciclasine alkaloids: Total synthesis of (+)- narciclasine and (+)-pancratistatin

Enantioselective total syntheses of the antimmor alkaloids, (+)- narciclasine and (+)-pancratistatin, are reported. These syntheses feature a stereo- and regiocontrolled aryl enamide photocyclization to construct a common, advanced intermediate possessing a transfused BC substructure. Differential functional group interchange in the C-ring of this phenanthridone core structure allows for the production of the two target natural products in enantiomerically pure form.