288403-03-2Relevant academic research and scientific papers
Ether type lipid a 1-carboxylic acid analogs
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, (2008/06/13)
A compound of formula (I) below, which exhibits excellent macrophage activity inhibitory action, is useful for the treatment or prophylaxis of inflammatory disorders, autoimmune diseases or septicemia. In a preferred embodiment, R1 and R3
Synthesis of lipid A type pyran carboxylic acids with ether chains and their biological activities
Watanabe, Yukiko,Mochizuki, Takashi,Shiozaki, Masao,Kanai, Saori,Kurakata, Shin-Ichi,Nishijima, Masahiro
, p. 203 - 231 (2007/10/03)
Synthesis of lipid A type pyran carboxylic acids having ether chains at both the C-3′ and C-4 positions and their bioactivities toward human U937 cells are described.
