288571-51-7

Basic information

• Product Name: 3-{2-[1-(4-Chloro-phenylsulfanyl)-meth-(E)-ylidene]-cyclohexyl}-propionitrile
• Synonyms: 3-{2-[1-(4-Chloro-phenylsulfanyl)-meth-(E)-ylidene]-cyclohexyl}-propionitrile
• CAS NO: 288571-51-7
• Molecular Weight: 291.845
• Mol File: 288571-51-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-{2-[1-(4-Chloro-phenylsulfanyl)-meth-(E)-ylidene]-cyclohexyl}-propionitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 3-{2-[1-(4-Chloro-phenylsulfanyl)-meth-(E)-ylidene]-cyclohexyl}-propionitrile(288571-51-7)
• EPA Substance Registry System: 3-{2-[1-(4-Chloro-phenylsulfanyl)-meth-(E)-ylidene]-cyclohexyl}-propionitrile(288571-51-7)

Safety Data

• Hazardous Substances Data: 288571-51-7(Hazardous Substances Data)

Upstream product

• 7205-90-5 chloromethyl 4-chlorophenyl sulfide 
• 4594-78-9 cyclohexanone-2-propionitrile 
• 181939-30-0 (4-chlorophenylmethyl)dimethylphosphonate 

Downstream Products

• 207114-39-4 4-{2-[1-(4-Chloro-phenylsulfanyl)-meth-(E)-ylidene]-cyclohexyl}-butan-2-one 

Relevant articles and documents

Antimalarial sulfide, sulfone, and sulfonamide trioxanes

A series of trioxanes featuring sulfide, sulfone, and sulfonamide substituents in diverse positions has been prepared. Structure-activity relationship (SAR) generalizations highlight two major factors controlling the antimalarial potency of these new chemical entities: (1) the proximity of the sulfur-containing substituent to the crucial peroxide bond and (2) the oxidation state of the sulfur-containing substituent. Generally, sulfones are more antimalarially potent than the corresponding sulfides. Copyright (C) 2000 Elsevier Science Ltd.