288574-50-5

Upstream product

• 288574-49-2 Benzoic acid (2R,3S,4S,5R)-4-hydroxy-3-iodo-5-methyl-tetrahydro-furan-2-ylmethyl ester 
• 288581-02-2 Benzoic acid (2S,4R,5R)-4-hydroxy-5-methyl-tetrahydro-furan-2-ylmethyl ester 
• 62-23-7 4-nitro-benzoic acid 
• 161807-42-7 (+)-(2E,4R,5R)-2,3-dihydroxyhex-2-enyl benzoate 
• 161807-32-5 (2E,4E)-hexa-2,4-dien-1-yl benzoate 

Relevant academic research and scientific papers

A brief synthesis of the Aplasmomycin tetrahydrofuran

A highly stereoselective iodocyclisation of the 3-alkene-1,2-diol 9, derived from asymmetric dihydroxylation of the dienyl benzoate 8, gives the β-iodotetrahydrofuran 10 and thence the Aplasmomycin precursor 13, following deiodination and Mitsunobu inversion. (C) 2000 Elsevier Science Ltd.