288580-32-5

Upstream product

• 132047-92-8 tert-butyl(pent-4-en-1-yloxy)diphenylsilane 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 111-29-5 1 ,5-pentanediol 
• 121671-76-9 5-(tert-butyldiphenylsilyloxy)pentan-1-ol 

Downstream Products

• 184535-06-6 (+)-(2R)-(2-oxopropyl)piperidine-1-carbamic acid benzyl ester 
• 87905-98-4 5-<(benzyloxycarbonyl)amino>pentanol 
• 69622-67-9 benzyl 2-hydroxypiperidine-1-carboxylate 
• 184535-17-9 (-)-(2S)-(2-oxopropyl)piperidine-1-carbamic acid benzyl ester 
• 1346132-32-8 (R)-N-benzyloxycarbonyl-2-(2-(4-nitrophenyl)-2-oxoethyl)piperidine 
• 1346132-31-7 (R)-N-benzyloxycarbonyl-2-(2-oxo-2-p-tolylethyl)piperidine 
• 405114-24-1 (R)-N-benzyloxycarbonyl-2-(2-oxo-2-phenylethyl)piperidine 
• 1346132-30-6 (R)-N-benzyloxycarbonyl-2-(4-methyl-2-oxopentyl)piperidine 
• 1346132-35-1 C₂₉H₃₇NO₃Si 
• 928657-99-2 C₆₀H₇₈N₂O₄Si₂ 
• 928657-98-1 C₅₈H₇₄N₂O₆Si₂ 

Relevant academic research and scientific papers

Iodine(III) reagent (ABX—N3)-induced intermolecular anti-Markovnikov hydroazidation of unactivated alkenes

Anti-Markovnikov hydroazidation of unactivated alkenes using ABX2014;N3 as an initiator has been developed at room temperature, wherein hydrogen azide (HN3) acts as both hydrogen and azidating agent. Notably, the HN3 reage

Asymmetric organocatalytic intramolecular aza-michael addition of enone carbamates: Catalytic enantioselective access to functionalized 2-substituted piperidines

The synthetically useful functionalized 2-substituted piperidines containing a lateral ketone group have been strategically accessed via an organocatalytic enantioselective intramolecular aza-Michael addition of enone carbamates, in which a novel internal substrate combination of the enone moiety as Michael acceptor and the carbamate moiety as Michael donor was revealed in asymmetric bifunctional organocatalysis. This heteroatom conjugate addition, which was realized by using a catalytic chiral Cinchona-based primary-tertiary diamine and an achiral Bronsted acid, mostly proceeded in high yield and good to excellent stereocontrol (up to 99% ee). This reaction provides an alternative catalytic asymmetric method for installing the stereogenic nitrogen-containing carbon center in functionalized 2-substituted piperidines, leading to the development of a straightforward and expeditious synthesis of some naturally occurring bioactive 2-substituted piperidine alkaloids. Copyright

Total synthesis of (+)-nakadomarin A

The total synthesis of (+)-nakadomarin A is described. A three-component cycloaddition of a hydroxylamine, aldehyde, and cyclopropane to form a highly functionalized tetrahydro-1,2-oxazine serves as the foundation for this synthesis. The resulting oxazine

A simple one-pot procedure for the direct conversion of alcohols to azides via phosphate activation

(Equation presented) A one-pot procedure was developed to prepare efficiently alkyl azides from alkanus using bis(2,4-dichlorophenyl) phosphate activation. 4-(Dimethylamino)pyridine was used as a base, and phosphorylpyridinium azide is believed to be the activating agent under this condition.