288591-99-1Relevant academic research and scientific papers
Rhodium(ii)-carbenoid C-H insertion reactions in the synthesis of β-oxospirane systems
Aburel, Pompiliu S.,Undheim, Kjell
, p. 1891 - 1896 (2000)
A simple one-pot procedure is described for the preparation of spiro[4.4]nonane-2,7-dione derivatives from open chain bis(α-diazoketones) by two consecutive intramolecular Rh(II)-catalyzed carbenoid insertion reactions. With 1-diazo-4-(3-oxocycloalkyl)butan-2-ones as substrates, the methodology provides 2,7-dioxospiranes with. a cyclopentane ring spiroannulated onto a five-, six- or seven-membered cycloalkane. The Royal Society of Chemistry 2000.
