28860-96-0 Usage
Uses
(αS)-α-Hydrazinyl-3,4-dimethoxy-α-methyl-benzenepropanoic Acid is an intermediate used in the synthesis of (S)-(-)-Carbidopa (C175985), which is a peripheral decarboxylase inhibitor that is commonly used in combination with L-DOPA (D533751) for treatment of Parkinsonism. S(-)-Carbidopa ( has also been shown to prolong the elimination half-life of L-DOPA from blood plasma and skeletal muscle.
Check Digit Verification of cas no
The CAS Registry Mumber 28860-96-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,8,8,6 and 0 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 28860-96:
(7*2)+(6*8)+(5*8)+(4*6)+(3*0)+(2*9)+(1*6)=150
150 % 10 = 0
So 28860-96-0 is a valid CAS Registry Number.
InChI:InChI=1/C12H18N2O4/c1-12(14-13,11(15)16)7-8-4-5-9(17-2)10(6-8)18-3/h4-6,14H,7,13H2,1-3H3,(H,15,16)
28860-96-0Relevant articles and documents
CARBIDOPA PRODRUGS AND USES THEREOF
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Page 71, (2010/02/07)
Prodrugs of carbidopa, derivatives of carbidopa prodrugs, methods of making prodrugs of carbidopa and derivatives thereof, methods of using prodrugs of carbidopa and derivatives thereof, and compositions of prodrugs of carbidopa and derivatives thereof are disclosed.