28863-87-8 Usage
Uses
Used in Medicinal Chemistry:
7-Benzyl-1,3,7-triazaspiro[4.4]nonane-2,4-dione is used as a chemical compound in medicinal chemistry for its potential biological activity. Its unique structure and properties allow it to be studied and developed for various therapeutic applications.
Used in Drug Discovery Research:
In drug discovery research, 7-benzyl-1,3,7-triazaspiro[4.4]nonane-2,4-dione is utilized as a starting point for the development of new drugs. Its unique structure and potential biological activity make it a valuable compound for exploring novel therapeutic agents.
Used in Pharmaceutical Industry:
7-Benzyl-1,3,7-triazaspiro[4.4]nonane-2,4-dione is used in the pharmaceutical industry as a potential active pharmaceutical ingredient (API) for the development of new medications. Its unique properties and potential applications in medicinal chemistry contribute to the advancement of drug discovery and therapeutic interventions.
Further research and study are required to fully understand the potential of 7-benzyl-1,3,7-triazaspiro[4.4]nonane-2,4-dione and its applications in various fields, including medicinal chemistry, drug discovery, and the pharmaceutical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 28863-87-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,8,8,6 and 3 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 28863-87:
(7*2)+(6*8)+(5*8)+(4*6)+(3*3)+(2*8)+(1*7)=158
158 % 10 = 8
So 28863-87-8 is a valid CAS Registry Number.
28863-87-8Relevant academic research and scientific papers
Microwave-assisted synthesis of functionalized spirohydantoins as 3-D privileged fragments for scouting the chemical space
Prevet, Hugues,Flipo, Marion,Roussel, Pascal,Deprez, Benoit,Willand, Nicolas
supporting information, p. 2888 - 2894 (2016/06/14)
Fragment-based drug design has been successfully applied to a large set of proteins, however in order to expand this concept to the most demanding targets, such as protein-protein interactions, it is required to enrich current fragment libraries with new and original 3D privileged fragments. Our goal was to develop a rapid microwave-assisted synthesis of 27 new privileged spirohydantoin fragments. Among them 24 compounds showed a high water solubility. These molecules were plotted according to the normalized principal moments of inertia of their minimized conformers, and most of the compounds were prone to occupy under-populated regions of the triangular plot. Finally we demonstrated that the hydantoin ring can be selectively N-monoalkylated providing the access to rapid functionalization for further elaboration.
