288862-58-8 Usage
Structure
Contains an oxazolo-pyridine ring system
Type
Synthetic chemical compound
Applications
Potential use in pharmaceutical research and drug development
Pharmacological activities
Anti-inflammatory, anti-cancer, and antimicrobial properties
Status
Promising candidate for the development of new drugs
Importance
Unique chemical structure and potential biological activities make it an interesting compound for further exploration in the field of medicinal chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 288862-58-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,8,8,8,6 and 2 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 288862-58:
(8*2)+(7*8)+(6*8)+(5*8)+(4*6)+(3*2)+(2*5)+(1*8)=208
208 % 10 = 8
So 288862-58-8 is a valid CAS Registry Number.
288862-58-8Relevant articles and documents
Inhibitors of fatty acid amide hydrolase
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, (2008/06/13)
Potent inhibitors of fatty acid amide hydrolase (FAAH) are constructed having Ki's below 200 pM and activities 102-103times more potent than the corresponding trifluoromethyl ketones. The potent inhibitors combine several features, viz.: 1.) an α-keto heterocylic head group; 2.) a hydrocarbon linkage unit employing an optimal C12-C8 chain length; and 3.) a phenyl or other π-unsaturation corresponding to the arachidonyl Δ8.9/Δ11.12and/or oleyl Δ9.10positions. A preferred α-keto heterocylic head group is α-keto N4 oxazolopyridine, with incorporation of a second weakly basic nitrogen. Fatty acid amide hydrolase is an enzyme responsible for the degradation of oleamide (an endogenous sleep-inducing lipid) and anandamide (an endogenous ligand for cannabinoid receptors).
