288862-73-7

Basic information

• Product Name: 1-OXAZOLO[4,5-B]PYRIDIN-2-YL-1-DODECANONE
• Synonyms: CAY10435;1-OXAZOLO[4,5-B]PYRIDIN-2-YL-1-DODECANONE;1-([1,3]oxazolo[4,5-b]pyridin-2-yl)dodecan-1-one
• CAS NO: 288862-73-7
• Molecular Formula: C18H26N2O2
• Molecular Weight: 302.41
• Mol File: 288862-73-7.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-OXAZOLO[4,5-B]PYRIDIN-2-YL-1-DODECANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-OXAZOLO[4,5-B]PYRIDIN-2-YL-1-DODECANONE(288862-73-7)
• EPA Substance Registry System: 1-OXAZOLO[4,5-B]PYRIDIN-2-YL-1-DODECANONE(288862-73-7)

Safety Data

• Hazardous Substances Data: 288862-73-7(Hazardous Substances Data)

Usage

Description

1-OXAZOLO[4,5-B]PYRIDIN-2-YL-1-DODECANONE is a complex organic compound with a unique molecular structure that features a pyridinyl-dodecanone moiety fused with an oxazolone ring. 1-OXAZOLO[4,5-B]PYRIDIN-2-YL-1-DODECANONE is characterized by its potential applications in various fields due to its specific chemical properties and interactions with other molecules.

Uses

Used in Pharmaceutical Industry:
1-OXAZOLO[4,5-B]PYRIDIN-2-YL-1-DODECANONE is used as a selective, potent inhibitor for the enzyme fatty acid amide hydrolase (FAAH) for the purpose of hydrolysis and inactivation of fatty acid amides, including anandamide and oleamide. 1-OXAZOLO[4,5-B]PYRIDIN-2-YL-1-DODECANONE, known as CAY10435, exhibits a high degree of specificity and potency with a Ki value of 0.57 nM, making it a valuable tool in the study and potential treatment of conditions related to FAAH activity.
Used in Research Applications:
In the field of research, 1-OXAZOLO[4,5-B]PYRIDIN-2-YL-1-DODECANONE, or CAY10435, is used as a valuable compound for screening and studying the serine hydrolase family of enzymes. 1-OXAZOLO[4,5-B]PYRIDIN-2-YL-1-DODECANONE has demonstrated IC50 values of 0.81 nM for FAAH, 83 nM for triacylglycerol hydrolase (TGH), and 50 μM for an uncharacterized hydrolase (KIAA1363), providing researchers with a means to investigate the roles and interactions of these enzymes in various biological processes.
Used in Drug Development:
1-OXAZOLO[4,5-B]PYRIDIN-2-YL-1-DODECANONE may also be utilized in the development of new drugs targeting FAAH and related enzymes. 1-OXAZOLO[4,5-B]PYRIDIN-2-YL-1-DODECANONE's high specificity and potency make it a promising candidate for the creation of therapeutic agents that can modulate the activity of these enzymes, potentially leading to treatments for a range of conditions influenced by FAAH activity.